ZNF639 and MPP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF639	MPP1
Description		zinc finger protein 639	MAGUK p55 scaffold protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoskeleton Plasma Membrane Cell-cell Junction Membrane Cortical Cytoskeleton Stereocilium Centriolar Satellite Cell Projection
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	GMP Kinase Activity Signaling Receptor Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Growth Host-mediated Suppression Of Viral Transcription Host-mediated Activation Of Viral Transcription Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Symbiont Entry Into Host Cell	Signal Transduction GMP Metabolic Process GDP Metabolic Process Regulation Of Neutrophil Chemotaxis
Pathways			Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Gout (normal type) ( 32238385) Response to antidepressants (symptom improvement) ( 29160301)	Hematology traits ( 23263863) Mean corpuscular volume ( 23263863) Red blood cell traits ( 23446634)
Interacting Genes		12 interacting genes: APTX CREBBP CRYAA MCRS1 MPP1 PNKP PRPF18 RIN3 ZBTB24 ZNF250 ZNF792 ZNF837	46 interacting genes: ABCC4 ACER1 ACER2 AGPAT3 AMOTL2 AP2M1 APH1A ATP5F1C ATRAID DERL2 DGAT2L6 DLG4 DNPEP ERBIN FXR2 GADD45A GPRASP3 GSK3B GYPC HNRNPD INCA1 KLHL12 MAP3K20 MEOX2 NR1H2 OGT OPTN PAQR8 PRIMPOL RPRM RPS6KA1 RPS6KA6 SGSM2 SLC35E1 SMN1 SRSF10 STK3 STUB1 SYNGR3 TK1 TMEM239 TRIM55 TRIM63 USP21 UXT ZNF639
Entrez ID		51193	4354
HPRD ID		15882	02370
Ensembl ID		ENSG00000121864	ENSG00000130830
Uniprot IDs		Q9UID6	B4E325 Q00013
PDB IDs			2EJY 2EV8 3NEY
Enriched GO Terms of Interacting Partners?		Polynucleotide 3'-phosphatase Activity Damaged DNA Binding Positive Regulation Of DNA Repair Histone Acetyltransferase Complex DNA Repair Regulation Of DNA Repair U2-type Post-spliceosomal Complex DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Negative Regulation Of Mast Cell Chemotaxis Positive Regulation Of DNA Metabolic Process Zinc Ion Binding DNA Metabolic Process Nucleus Histone H3K27 Acetyltransferase Activity Generation Of Catalytic Spliceosome For Second Transesterification Step Positive Regulation Of Telomere Maintenance ATP-dependent Polynucleotide 5'-hydroxyl-kinase Activity Phosphoglycolate Phosphatase Activity Positive Regulation Of Double-strand Break Repair Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation DNA Damage Response Regulation Of Protein Stability Positive Regulation Of Protein Localization To Nucleus Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity MRF Binding Response To Radiation Regulation Of Transcription By RNA Polymerase II Centriolar Satellite RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Purine Nucleotide Binding Double-stranded DNA Binding Positive Regulation Of Protein Localization To Nucleolus Regulation Of DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Double-strand Break Repair Regulation Of Cellular Response To Stress Response To UV Metal Ion Binding Regulation Of Protein Localization To Nucleus Lens Fiber Cell Morphogenesis Poly(G) Binding Telomerase Inhibitor Activity G-quadruplex RNA Binding Regulation Of Mast Cell Chemotaxis	Intracellular Signal Transduction TOR Signaling Ribosomal Protein S6 Kinase Activity N-acylsphingosine Amidohydrolase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?