TUBE1 and CDC40

		TUBE1	CDC40
Description		tubulin epsilon 1	cell division cycle 40
Image		No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Cytoskeleton Microtubule Microtubule Cytoskeleton	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Structural Constituent Of Cytoskeleton GTP Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Centrosome Cycle	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Embryonic Brain Development
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Vinblastine
Diseases
GWAS			Daytime sleep phenotypes ( 27126917)
Interacting Genes		6 interacting genes: CDC40 DPAGT1 GOPC MTRES1 NUDC RPS20	10 interacting genes: CRYAA DHX38 EPS15 MIR106B MIRLET7A2 MIRLET7E MIRLET7G SMAD2 SMURF1 TUBE1
Entrez ID		51175	51362
HPRD ID		06298	05721
Ensembl ID		ENSG00000074935	ENSG00000168438
Uniprot IDs		Q9UJT0	O60508
PDB IDs			5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P 7AAV 7ABI 7W59 7W5A 7W5B 8C6J 8CH6 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity Negative Regulation Of Anion Channel Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Transforming Growth Factor Beta Receptor Binding I-SMAD Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway R-SMAD Binding Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell MiRNA-mediated Gene Silencing By MRNA Destabilization Post-transcriptional Regulation Of Gene Expression SMAD Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Engulfment Of Target By Autophagosome Negative Regulation Of Biosynthetic Process Regulation Of Cellular Response To Growth Factor Stimulus Homomeric SMAD Protein Complex Negative Regulation Of Macromolecule Metabolic Process MRNA Destabilization Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway RNA Destabilization Regulation Of BMP Signaling Pathway Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Metabolic Process Response To Glucose Embryonic Organ Morphogenesis Regulation Of Macromolecule Metabolic Process Response To Monosaccharide Mesoderm Morphogenesis Positive Regulation Of Cell Growth Lens Fiber Cell Morphogenesis Ubiquitin-dependent Endocytosis Clathrin Coat Of Coated Pit Response To Carbohydrate Odontoblast Differentiation SMAD Protein Complex Pericardium Development Trophoblast Cell Migration 3'-5' RNA Helicase Activity Activin Receptor Binding Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Catabolic Process
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