REG3A and IGKC

		REG3A	IGKC
Description		regenerating family member 3 alpha	immunoglobulin kappa constant
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Extracellular Region Extracellular Space Plasma Membrane Membrane Immunoglobulin Complex Extracellular Exosome IgG Immunoglobulin Complex IgD Immunoglobulin Complex IgE Immunoglobulin Complex IgA Immunoglobulin Complex IgM Immunoglobulin Complex Blood Microparticle
	Molecular Function	Hormone Activity Protein Binding Carbohydrate Binding Signaling Receptor Activity Identical Protein Binding Peptidoglycan Binding Oligosaccharide Binding	Antigen Binding
	Biological Process	Acute-phase Response Inflammatory Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Cell Population Proliferation Response To Symbiotic Bacterium Response To Wounding Positive Regulation Of Keratinocyte Proliferation Response To Peptide Hormone Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Positive Regulation Of Wound Healing Inflammatory Response To Wounding Negative Regulation Of Inflammatory Response To Wounding Positive Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Detection Of Glucose	Adaptive Immune Response Immune System Process Immune Response Immunoglobulin Mediated Immune Response B Cell Receptor Signaling Pathway
Pathways		Antimicrobial peptides
Drugs
Diseases
GWAS		Body mass index ( 25673413) HDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		7 interacting genes: ANXA3 FN1 IGKC MDFI REG1A SDC2 TRHDE	7 interacting genes: CD40LG CFTR IGHG1 MLH1 PLGLB2 REG3A SMARCD1
Entrez ID		5068	3514
HPRD ID		01342	00921
Ensembl ID		ENSG00000172016	ENSG00000211592
Uniprot IDs		Q06141 Q53S56
PDB IDs		1UV0 2GO0 4MTH
Enriched GO Terms of Interacting Partners?			Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Somatic Recombination Of Immunoglobulin Gene Segments Positive Regulation Of Lymphocyte Activation B Cell Activation Involved In Immune Response Positive Regulation Of Immune System Process Somatic Cell DNA Recombination Immune Effector Process Regulation Of Immunoglobulin Production Somatic Diversification Of Immunoglobulins Positive Regulation Of Cell Activation Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Acute Inflammatory Response Response To Bacterium Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Positive Regulation Of Gene Expression CD40 Receptor Binding Positive Regulation Of Anion Channel Activity Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Positive Regulation Of Detection Of Glucose Regulation Of Lymphocyte Activation Inflammatory Response Lymphocyte Activation Involved In Immune Response Positive Regulation Of Monoatomic Anion Transport Complement-dependent Cytotoxicity Fc-gamma Receptor I Complex Binding Male Meiosis Chromosome Segregation MutLalpha Complex Leukocyte Activation Involved In Immune Response Regulation Of Cell Activation Positive Regulation Of Enamel Mineralization Guanine/thymine Mispair Binding Negative Regulation Of Mitotic Recombination Cell Activation Involved In Immune Response Antimicrobial Humoral Response Regulation Of Immune System Process Transepithelial Water Transport Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Mismatch Repair Complex Response To Symbiotic Bacterium Response To Symbiont Regulation Of Multicellular Organismal Process Positive Regulation Of Multicellular Organismal Process
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