IGKC and PLGLB2

		IGKC	PLGLB2
Description		immunoglobulin kappa constant	plasminogen like B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Immunoglobulin Complex Extracellular Exosome IgG Immunoglobulin Complex IgD Immunoglobulin Complex IgE Immunoglobulin Complex IgA Immunoglobulin Complex IgM Immunoglobulin Complex Blood Microparticle	Extracellular Region
	Molecular Function	Antigen Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Immunoglobulin Mediated Immune Response B Cell Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Mitochondrial heteroplasmy measurement ( 33731350)
Interacting Genes		7 interacting genes: CD40LG CFTR IGHG1 MLH1 PLGLB2 REG3A SMARCD1	1 interacting genes: IGKC
Entrez ID		3514	5342
HPRD ID		00921	01416
Ensembl ID		ENSG00000211592	ENSG00000125551
Uniprot IDs			Q02325
PDB IDs
Enriched GO Terms of Interacting Partners?		Isotype Switching Somatic Diversification Of Immunoglobulins Involved In Immune Response Somatic Recombination Of Immunoglobulin Genes Involved In Immune Response Somatic Recombination Of Immunoglobulin Gene Segments Positive Regulation Of Lymphocyte Activation B Cell Activation Involved In Immune Response Positive Regulation Of Immune System Process Somatic Cell DNA Recombination Immune Effector Process Regulation Of Immunoglobulin Production Somatic Diversification Of Immunoglobulins Positive Regulation Of Cell Activation Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Acute Inflammatory Response Response To Bacterium Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Positive Regulation Of Gene Expression CD40 Receptor Binding Positive Regulation Of Anion Channel Activity Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Positive Regulation Of Detection Of Glucose Regulation Of Lymphocyte Activation Inflammatory Response Lymphocyte Activation Involved In Immune Response Positive Regulation Of Monoatomic Anion Transport Complement-dependent Cytotoxicity Fc-gamma Receptor I Complex Binding Male Meiosis Chromosome Segregation MutLalpha Complex Leukocyte Activation Involved In Immune Response Regulation Of Cell Activation Positive Regulation Of Enamel Mineralization Guanine/thymine Mispair Binding Negative Regulation Of Mitotic Recombination Cell Activation Involved In Immune Response Antimicrobial Humoral Response Regulation Of Immune System Process Transepithelial Water Transport Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Mismatch Repair Complex Response To Symbiotic Bacterium Response To Symbiont Regulation Of Multicellular Organismal Process Positive Regulation Of Multicellular Organismal Process	IgD Immunoglobulin Complex IgA Immunoglobulin Complex IgM Immunoglobulin Complex IgE Immunoglobulin Complex IgG Immunoglobulin Complex Immunoglobulin Complex Antigen Binding Immunoglobulin Mediated Immune Response B Cell Mediated Immunity B Cell Receptor Signaling Pathway Lymphocyte Mediated Immunity Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Blood Microparticle Antigen Receptor-mediated Signaling Pathway Leukocyte Mediated Immunity Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Adaptive Immune Response Immune Response-activating Signaling Pathway Immune Response-regulating Signaling Pathway Immune Effector Process Activation Of Immune Response
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