IL20 and S100P

Number of citations of the paper that reports this interaction (PubMedID 36233301)
61

Data Source:
BioGRID (pull down)

		IL20	S100P
Description		interleukin 20	S100 calcium binding protein P
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Cytokine Activity Protein Binding Interleukin-20 Receptor Binding Interleukin-22 Receptor Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding
	Biological Process	Immune Response Signal Transduction Osteoclast Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Osteoclast Differentiation Regulation Of Inflammatory Response	Endothelial Cell Migration
Pathways		Interleukin-20 family signaling	Neutrophil degranulation
Drugs			Cromoglicic acid
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: IL20RA S100A6 S100P	48 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP MAD1L1 OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A WFS1
Entrez ID		50604	6286
HPRD ID		05728	02792
Ensembl ID		ENSG00000162891	ENSG00000163993
Uniprot IDs		A0A7R8C4W0 Q9NYY1	P25815
PDB IDs		4DOH	1J55 1OZO 2MJW 7NMI
Enriched GO Terms of Interacting Partners?		Calcium-dependent Protein Binding Interleukin-20 Binding Monoatomic Ion Transmembrane Transporter Activity Tropomyosin Binding S100 Protein Binding Calcium Ion Binding Transition Metal Ion Binding Protein Homodimerization Activity Microvillus Membrane	Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation
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