IL20 and IL20RA

Number of citations of the paper that reports this interaction (PubMedID 14580208)
0

Data Source:
HPRD (in vivo)

		IL20	IL20RA
Description		interleukin 20	interleukin 20 receptor subunit alpha
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Protein Binding Interleukin-20 Receptor Binding Interleukin-22 Receptor Binding	Cytokine Receptor Activity Protein Binding Interleukin-20 Binding
	Biological Process	Immune Response Signal Transduction Osteoclast Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Osteoclast Differentiation Regulation Of Inflammatory Response	Cytokine-mediated Signaling Pathway Regulation Of Bone Resorption Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Interleukin-20 family signaling	Interleukin-20 family signaling
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Multiple sclerosis ( 31604244) Type 2 diabetes ( 24509480)
Interacting Genes		3 interacting genes: IL20RA S100A6 S100P	3 interacting genes: IL19 IL20 IL24
Entrez ID		50604	53832
HPRD ID		05728	05729
Ensembl ID		ENSG00000162891	ENSG00000016402
Uniprot IDs		A0A7R8C4W0 Q9NYY1	Q9UHF4
PDB IDs		4DOH	4DOH
Enriched GO Terms of Interacting Partners?		Calcium-dependent Protein Binding Interleukin-20 Binding Monoatomic Ion Transmembrane Transporter Activity Tropomyosin Binding S100 Protein Binding Calcium Ion Binding Transition Metal Ion Binding Protein Homodimerization Activity Microvillus Membrane	Cytokine Activity Immune Response Interleukin-20 Receptor Binding Interleukin-22 Receptor Binding Extracellular Space Immune System Process Extracellular Region Negative Regulation Of Low-density Lipoprotein Particle Clearance Cellular Response To Interleukin-4 Response To Interleukin-4 Regulation Of Low-density Lipoprotein Particle Clearance Negative Regulation Of Lipoprotein Particle Clearance Positive Regulation Of Osteoclast Differentiation Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Epidermis Development Regulation Of Keratinocyte Differentiation
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