S100P and UBL4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		S100P	UBL4A
Description		S100 calcium binding protein P	ubiquitin like 4A
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Plasma Membrane Membrane Microvillus Membrane Secretory Granule Lumen Cell Projection Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane BAT3 Complex
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Protein-folding Chaperone Binding
	Biological Process	Endothelial Cell Migration	Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Protein Stability Protein Modification Process Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways		Neutrophil degranulation	Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Cromoglicic acid
Diseases
GWAS		Obesity-related traits ( 23251661)	Neutrophil count ( 32888494)
Interacting Genes		48 interacting genes: AGER ARC CACYBP CEBPA CLCF1 CNTF CSF2 CSF3 CTF1 EBI3 EPO EZR GH1 GH2 IFNB1 IFNW1 IL10 IL11 IL12A IL13 IL15 IL20 IL21 IL22 IL24 IL26 IL27 IL3 IL31 IL5 IL9 LEP MAD1L1 OSM PRL S100A1 S100A2 S100A4 S100B S100Z STUB1 SUGT1 TERF2IP TFIP11 TGFBI THPO UBL4A WFS1	14 interacting genes: AMFR APP CDCA7L ERP27 MEOX2 MYH10 PER2 RNF126 S100P SGTA SGTB TRAF4 TRIM54 USP13
Entrez ID		6286	8266
HPRD ID		02792	02417
Ensembl ID		ENSG00000163993	ENSG00000102178
Uniprot IDs		P25815	P11441
PDB IDs		1J55 1OZO 2MJW 7NMI	2DZI 4WWR 4X86 7RU9 7RUA 7RUC
Enriched GO Terms of Interacting Partners?		Cytokine Activity Extracellular Space Cytokine-mediated Signaling Pathway Extracellular Region Growth Factor Activity Positive Regulation Of Cell Population Proliferation Regulation Of Cell Population Proliferation Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Cytokine Receptor Binding Cell Surface Receptor Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Multicellular Organismal Process Regulation Of Receptor Signaling Pathway Via JAK-STAT Leukocyte Differentiation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Lymphocyte Activation Positive Regulation Of Developmental Process Regulation Of Cell Activation Immune System Process Cell Activation Positive Regulation Of Metabolic Process Leukocyte Activation S100 Protein Binding Positive Regulation Of Protein Modification Process Positive Regulation Of Cell Activation Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cytokine Production Immune Response Positive Regulation Of Phosphorylation Positive Regulation Of Gene Expression Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Proliferation Positive Regulation Of Protein Metabolic Process Regulation Of Cytokine Production Regulation Of Developmental Process Regulation Of Protein Phosphorylation Regulation Of T Cell Activation	BAT3 Complex Binding TRC Complex Protein-folding Chaperone Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Cellular Response To Stress Regulation Of Response To Endoplasmic Reticulum Stress Protein K27-linked Ubiquitination Positive Regulation Of ERAD Pathway Transition Metal Ion Binding Regulation Of Neurotransmitter Uptake Growth Cone Regulation Of ERAD Pathway Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Response To Endoplasmic Reticulum Stress Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway
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