ACO2 and LINC00632

Number of citations of the paper that reports this interaction (PubMedID 36527092)
63

Data Source:
BioGRID (unspecified method)

		ACO2	LINC00632
Description		aconitase 2	long intergenic non-protein coding RNA 632
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol
	Molecular Function	Aconitate Hydratase Activity Iron Ion Binding Lyase Activity Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle Citrate Metabolic Process
Pathways		Mitochondrial protein import Citric acid cycle (TCA cycle) Mitochondrial protein degradation Maturation of TCA enzymes and regulation of TCA cycle
Drugs		Isocitric Acid 4-Hydroxy-Aconitate Ion Alpha-Methylisocitric Acid Aconitate Ion Tricarballylic acid
Diseases
GWAS		Adult body size ( 32376654) Asthma ( 32296059) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		8 interacting genes: APP ATXN1L C5AR2 CD244 CDC42 LINC00632 RNF10 SUMO4	37 interacting genes: ACO2 ACTR2 ANP32A ANXA6 ARF3 ASPH CTSB DYNC1LI2 ELAVL1 GDI1 GDI2 GNB1 HSPE1 ITGA3 LAP3 LGALS3 LMAN1 MDH2 MXRA7 PAICS PFKP PGD PGRMC1 PGRMC2 PSMA1 PXN RAB1B RECQL RPLP0 RPN2 RRAS2 SF1 STMN1 TGFBI TPM1 TUBA1C UGDH
Entrez ID		50	286411
HPRD ID		00012
Ensembl ID		ENSG00000100412	ENSG00000203930
Uniprot IDs		Q99798
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Neuron Projection Organization Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Regulation Of Type II Interferon Production Cell Activation Involved In Immune Response Dendrite Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Regulation Of Interleukin-6 Production Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Postsynapse Organization Positive Regulation Of Type II Interferon Production Positive Regulation Of Small Molecule Metabolic Process Learning Lipoprotein Particle Memory Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Regulation Of Nervous System Process Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Apolipoprotein A-I Receptor Binding Endothelin Receptor Signaling Pathway Involved In Heart Process Apical Part Of Cell Neuropilin Signaling Pathway GBD Domain Binding Storage Vacuole Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Complement Component C5a Receptor Activity Regulation Of Interleukin-8 Production Complement Component C5a Signaling Pathway	Extracellular Exosome Focal Adhesion Rab GDP-dissociation Inhibitor Activity
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