LINC00632 and TGFBI

Number of citations of the paper that reports this interaction (PubMedID 36527092)
63

Data Source:
BioGRID (unspecified method)

		LINC00632	TGFBI
Description		long intergenic non-protein coding RNA 632	transforming growth factor beta induced
Image		No pdb structure
GO Annotations	Cellular Component		Extracellular Region Basement Membrane Extracellular Space Trans-Golgi Network Plasma Membrane Extracellular Matrix Extracellular Exosome Cell Periphery
	Molecular Function		Integrin Binding Extracellular Matrix Structural Constituent Protein Binding Collagen Binding Identical Protein Binding Cell Adhesion Molecule Binding Extracellular Matrix Binding
	Biological Process		Angiogenesis Chondrocyte Differentiation Cell Adhesion Negative Regulation Of Cell Adhesion Visual Perception Cell Population Proliferation Extracellular Matrix Organization
Pathways			Amyloid fiber formation
Drugs
Diseases			Reis-Bucklers corneal dystrophy (RBCD); Corneal dystrophy of Bowman's type I; Granular corneal dystrophy type III Lattice corneal dystrophies (LCD), including: Biber-Haab-Dimmer dystrophy; Familial amyloid polyneuropathy type IV; Meretoja syndrome Thiel-Behnke dystrophies (TBCD); Corneal dystrophy of Bowman layer type II; Honeycomb corneal dystrophy; Anterior limiting membrane dystrophy type II; Curly fibers corneal dystrophy; Waardenburg-Jonker corneal dystrophy Granular corneal dystrophies (GCD), including: Corneal dystrophy Groenouw type I; Avellino corneal dystrophy; Granular-lattice dystrophy
GWAS			Blood protein levels ( 30072576) Insomnia ( 27992416) Response to cytidine analogues (gemcitabine) ( 24483146) Stroke ( 26089329)
Interacting Genes		37 interacting genes: ACO2 ACTR2 ANP32A ANXA6 ARF3 ASPH CTSB DYNC1LI2 ELAVL1 GDI1 GDI2 GNB1 HSPE1 ITGA3 LAP3 LGALS3 LMAN1 MDH2 MXRA7 PAICS PFKP PGD PGRMC1 PGRMC2 PSMA1 PXN RAB1B RECQL RPLP0 RPN2 RRAS2 SF1 STMN1 TGFBI TPM1 TUBA1C UGDH	16 interacting genes: A2M COL1A1 COL1A2 COL2A1 COL4A1 COL4A2 COL4A3 COL4A4 FAM9B FBXL17 FN1 LINC00632 LINC01554 MMP9 POR S100P
Entrez ID		286411	7045
HPRD ID			03409
Ensembl ID		ENSG00000203930	ENSG00000120708
Uniprot IDs			A0A0S2Z4Q2 Q15582
PDB IDs			1X3B 2LTB 2LTC 2VXP 5NV6 7AS7 7ASC 7ASG 8HGA 8HIA
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Focal Adhesion Rab GDP-dissociation Inhibitor Activity	Extracellular Matrix Structural Constituent Conferring Tensile Strength Extracellular Matrix Structural Constituent Collagen Trimer Extracellular Matrix Collagen Type IV Trimer Extracellular Matrix Organization Extracellular Structure Organization Endoplasmic Reticulum Lumen Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Platelet-derived Growth Factor Binding Basement Membrane Collagen-activated Signaling Pathway Fibrillar Collagen Trimer Extracellular Region Collagen Type I Trimer Protease Binding Endodermal Cell Differentiation Enzyme-linked Receptor Protein Signaling Pathway Skeletal System Development Collagen Fibril Organization Collagen Metabolic Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Glomerular Basement Membrane Development Cellular Response To Amino Acid Stimulus Skin Morphogenesis Proteoglycan Binding Cartilage Development Involved In Endochondral Bone Morphogenesis Response To Amino Acid Cell Surface Receptor Signaling Pathway Developmental Process System Development Sensory Perception Of Sound Endochondral Ossification Sensory Perception Of Mechanical Stimulus Cellular Developmental Process Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Cellular Response To Vitamin E Protein Heterotrimerization Iron-cytochrome-c Reductase Activity Positive Regulation Of Growth Plate Cartilage Chondrocyte Proliferation Nitric Oxide Dioxygenase NAD(P)H Activity Nitrate Catabolic Process Extracellular Space Cellular Response To Transforming Growth Factor Beta Stimulus Platelet Alpha Granule Lumen Collagen Binding Negative Regulation Of Complement Activation, Lectin Pathway Cellular Response To Fluoride Nitric Oxide Catabolic Process
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