NFIC and TPD52L3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NFIC	TPD52L3
Description		nuclear factor I C	TPD52 like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Fibrillar Center Nucleus Nucleoplasm	Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Odontogenesis Of Dentin-containing Tooth Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Alzheimer's disease (APOE e4 interaction) ( 28183528) Apolipoprotein A1 levels ( 32203549) Appendicular lean mass ( 33097823) Automobile speeding propensity ( 30643258) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Heel bone mineral density ( 30598549) Height ( 20881960 31562340 28552196 25282103) High light scatter reticulocyte count ( 32888494) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Monocyte count ( 32888494) Nevus count or cutaneous melanoma ( 30429480) Platelet count ( 32888494) Plateletcrit ( 32888494) Serum urate levels in chronic kidney disease ( 30181573) Weight ( 28552196) Youthful appearance (self-reported) ( 32339537)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474 31959851) Asthma (childhood onset) ( 29273806) Asthma or allergic disease (pleiotropy) ( 29785011) Eosinophil percentage of white cells ( 32888494) Hemoglobin levels ( 32327693) Metabolite levels ( 23823483) Periodontal microbiota ( 22699663) Red blood cell count ( 32888494)
Interacting Genes		55 interacting genes: CBLC CREBBP ELK3 EPHA2 ERG ERGIC1 ETV7 FBXO7 FOS FOXL1 GATA2 GATA3 GLIS1 GLIS2 GLRX KLF16 KLF8 LATS2 LHX2 LHX3 LHX4 LLPH MAP2K3 MAPK14 MYC NFIB NSD3 PAX2 PAX6 PAX7 PAX8 PRDM1 RFX1 SFN SOX10 SOX15 SOX17 SOX2 SOX3 SOX5 SOX6 SOX9 SP7 TBR1 TBXT TEAD2 TKTL2 TLX1 TLX2 TLX3 TPD52L3 UBC YY1 ZCCHC14 ZKSCAN7	9 interacting genes: AGTRAP APP CMTM5 NFIC TPD52 TPD52L1 TPD52L2 TRIM55 TRIM63
Entrez ID		4782	89882
HPRD ID		09009	14864
Ensembl ID		ENSG00000141905	ENSG00000170777
Uniprot IDs		B7Z4T6 P08651	A0A140VKH0 Q96J77
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Animal Organ Development Cellular Developmental Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Cis-regulatory Region Binding Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Neuron Differentiation Nucleus Sequence-specific DNA Binding Cell Fate Specification Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Developmental Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Developmental Process Positive Regulation Of Metabolic Process Cell Fate Commitment Regulation Of Cell Differentiation Anatomical Structure Morphogenesis Negative Regulation Of Developmental Process Regulation Of MiRNA Transcription Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Regulation Of MiRNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process	Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Homodimerization Activity Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Acetylcholine Receptor Activator Activity PTB Domain Binding Response To Interleukin-1 Regulation Of ATP Metabolic Process Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of JNK Cascade Regulation Of Purine Nucleotide Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Regulation Of Phosphorus Metabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Regulation Of Generation Of Precursor Metabolites And Energy Low-density Lipoprotein Particle Mediated Signaling Angiotensin Type II Receptor Activity Skeletal Muscle Atrophy Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Diapedesis
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