MT1H and SPINK7

Number of citations of the paper that reports this interaction (PubMedID 12970870)
34

Data Source:
HPRD (two hybrid)

		MT1H	SPINK7
Description		metallothionein 1H	serine peptidase inhibitor Kazal type 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Intracellular Zinc Ion Homeostasis Detoxification Of Copper Ion Negative Regulation Of Growth Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion	Inflammatory Response Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways		Metallothioneins bind metals
Drugs		Silver
Diseases
GWAS		Gambling ( 22780124)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Experiencing mood swings ( 29500382)
Interacting Genes		4 interacting genes: PRKAR2B RNF181 SERPINB5 SPINK7	9 interacting genes: EPB42 FTL GALNT10 HBA1 MRPS12 MT1G MT1H MT2A RABL6
Entrez ID		4496	84651
HPRD ID		01128	16850
Ensembl ID		ENSG00000205358	ENSG00000145879
Uniprot IDs		A0A140VJP7 P80294	P58062
PDB IDs			2LEO
Enriched GO Terms of Interacting Partners?		Serine-type Endopeptidase Inhibitor Activity Response To Antipsychotic Drug Prostate Gland Morphogenesis CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Regulator Activity CAMP-dependent Protein Kinase Inhibitor Activity	Detoxification Of Copper Ion Cellular Response To Cadmium Ion Cellular Response To Zinc Ion Cellular Response To Copper Ion Intracellular Zinc Ion Homeostasis Response To Copper Ion Inorganic Ion Homeostasis Response To Cadmium Ion Response To Zinc Ion Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Chemical Homeostasis Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Cellular Response To Metal Ion Intracellular Chemical Homeostasis Negative Regulation Of Growth Cellular Homeostasis Homeostatic Process Response To Metal Ion Ferritin Complex Iron Ion Binding Haptoglobin Binding Cellular Response To Erythropoietin Nitric Oxide Transport Response To Erythropoietin Regulation Of Growth Ankyrin-1 Complex Protein-glutamine Gamma-glutamyltransferase Activity Ferric Iron Binding Cellular Response To Interleukin-3 Metal Ion Binding Monocyte Activation Hemoglobin Metabolic Process Haptoglobin-hemoglobin Complex Autolysosome Hemoglobin Complex Oxygen Carrier Activity Polypeptide N-acetylgalactosaminyltransferase Activity Carbon Dioxide Transport Intracellular Copper Ion Homeostasis Oxygen Transport Erythrocyte Maturation Hydrogen Peroxide Catabolic Process Endocytic Vesicle Lumen Monocyte Differentiation Copper Ion Homeostasis Ferrous Iron Binding Multicellular Organismal-level Iron Ion Homeostasis One-carbon Compound Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?