NDUFS7 and DPCD

		NDUFS7	DPCD
Description		NADH:ubiquinone oxidoreductase core subunit S7	deleted in primary ciliary dyskinesia homolog (mouse)
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Neuronal Cell Body Respiratory Chain Complex I Synaptic Membrane	Extracellular Region Nucleus
	Molecular Function	Protease Binding NADH Dehydrogenase Activity Monooxygenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Protein Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Ventricular System Development Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Establishment Of Localization In Cell Left/right Pattern Formation
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Mean corpuscular volume ( 32888494)
Interacting Genes		4 interacting genes: ARRB2 DPCD ENO2 MT-ND1	13 interacting genes: ACTR1A APP BTRC CNNM2 CUEDC2 GUCA2B HACD3 MNDA NDUFS7 NOLC1 PPRC1 RUVBL2 WBP1L
Entrez ID		374291	25911
HPRD ID		03491	13247
Ensembl ID		ENSG00000115286	ENSG00000166171
Uniprot IDs		F5H5N1 O75251 Q6ZS38 Q7LD69	Q5JQQ4 Q9BVM2
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Angiotensin Receptor Binding Positive Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Synaptic Transmission, Dopaminergic D1 Dopamine Receptor Binding Negative Adaptation Of Signaling Pathway Desensitization Of G Protein-coupled Receptor Signaling Pathway Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Response To Xenobiotic Stimulus Phosphopyruvate Hydratase Complex Purine Ribonucleotide Metabolic Process Phosphopyruvate Hydratase Activity ATP Metabolic Process Generation Of Precursor Metabolites And Energy Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Third Ventricle Development Positive Regulation Of Cardiac Muscle Cell Differentiation Protein Kinase B Binding Purine Nucleotide Metabolic Process Neuronal Cell Body NADH Dehydrogenase Activity Enzyme Binding G Protein-coupled Receptor Internalization Nucleotide Metabolic Process Lateral Ventricle Development Left/right Pattern Formation Positive Regulation Of Cardiocyte Differentiation
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