DPCD and NDUFS7

		DPCD	NDUFS7
Description		deleted in primary ciliary dyskinesia homolog (mouse)	NADH:ubiquinone oxidoreductase core subunit S7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Neuronal Cell Body Respiratory Chain Complex I Synaptic Membrane
	Molecular Function	Protein Binding	Protease Binding NADH Dehydrogenase Activity Monooxygenase Activity Protein Binding NADH Dehydrogenase (ubiquinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Metal Ion Binding Quinone Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Epithelial Cilium Movement Involved In Extracellular Fluid Movement Spermatogenesis Determination Of Left/right Symmetry Ventricular System Development Lateral Ventricle Development Third Ventricle Development Flagellated Sperm Motility Establishment Of Localization In Cell Left/right Pattern Formation	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Electron Transport Coupled Proton Transport Mitochondrial Respiratory Chain Complex I Assembly Proton Motive Force-driven Mitochondrial ATP Synthesis
Pathways			Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Mean corpuscular volume ( 32888494)
Interacting Genes		13 interacting genes: ACTR1A APP BTRC CNNM2 CUEDC2 GUCA2B HACD3 MNDA NDUFS7 NOLC1 PPRC1 RUVBL2 WBP1L	4 interacting genes: ARRB2 DPCD ENO2 MT-ND1
Entrez ID		25911	374291
HPRD ID		13247	03491
Ensembl ID		ENSG00000166171	ENSG00000115286
Uniprot IDs		Q5JQQ4 Q9BVM2	F5H5N1 O75251 Q6ZS38 Q7LD69
PDB IDs			5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?			Angiotensin Receptor Binding Positive Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Synaptic Transmission, Dopaminergic D1 Dopamine Receptor Binding Negative Adaptation Of Signaling Pathway Desensitization Of G Protein-coupled Receptor Signaling Pathway Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Response To Xenobiotic Stimulus Phosphopyruvate Hydratase Complex Purine Ribonucleotide Metabolic Process Phosphopyruvate Hydratase Activity ATP Metabolic Process Generation Of Precursor Metabolites And Energy Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Third Ventricle Development Positive Regulation Of Cardiac Muscle Cell Differentiation Protein Kinase B Binding Purine Nucleotide Metabolic Process Neuronal Cell Body NADH Dehydrogenase Activity Enzyme Binding G Protein-coupled Receptor Internalization Nucleotide Metabolic Process Lateral Ventricle Development Left/right Pattern Formation Positive Regulation Of Cardiocyte Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?