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IGFBP6 and MSGN1
Data Source:
BioGRID
(two hybrid)
IGFBP6
MSGN1
Description
insulin like growth factor binding protein 6
mesogenin 1
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Golgi Apparatus
Insulin-like Growth Factor Binary Complex
Chromatin
Nucleus
Molecular Function
Fibronectin Binding
Signaling Receptor Binding
Protein Binding
Insulin-like Growth Factor I Binding
Insulin-like Growth Factor II Binding
Identical Protein Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
Protein Binding
Protein Dimerization Activity
Sequence-specific Double-stranded DNA Binding
Biological Process
Activation Of MAPK Activity
Signal Transduction
Negative Regulation Of Cell Population Proliferation
Cell Migration
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Cellular Protein Metabolic Process
Negative Regulation Of Canonical Wnt Signaling Pathway
Mesoderm Formation
Somitogenesis
Regulation Of Transcription By RNA Polymerase II
Segment Specification
Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs
Diseases
GWAS
Disease progression in age-related macular degeneration (adjusted for baseline) (
29346644
)
Metabolite levels (
23823483
)
Interacting Genes
37 interacting genes:
ALPP
ANKRD11
AQP1
C1orf74
CCDC116
CCDC28A
CDIPT
CREB5
EFEMP1
EFEMP2
ENKD1
EPDR1
GAS8
GET3
IGF1
IGF2
KRTAP10-8
KRTAP5-7
KRTAP5-9
MBD3
MEIS2
MSGN1
NCALD
PLEKHA7
POU4F2
RABGGTB
RANBP10
SDCBP
SGTA
SMCP
TF
UBAC1
UBQLN1
UBQLN2
UBQLN4
ZNF417
ZNF587
30 interacting genes:
AP1B1
ATP11B
BRAT1
CCDC172
CTAG1A
CTAG1B
DNALI1
EXOC7
FERD3L
HAP1
ID1
ID2
ID3
IGFBP6
ITGB3BP
LDOC1
MAGEA6
MYF5
MYL9
NECAB2
OST4
SERTAD3
TCF12
TCF4
TEPSIN
TEX12
TRAF1
TTC23L
ZMYND12
ZWINT
Entrez ID
3489
343930
HPRD ID
00902
Ensembl ID
ENSG00000167779
ENSG00000151379
Uniprot IDs
P24592
A6NI15
PDB IDs
1RMJ
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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