MSGN1 and CCDC172

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSGN1	CCDC172
Description		mesogenin 1	coiled-coil domain containing 172
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Cilium Cell Projection Sperm Midpiece
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Mesoderm Formation Somitogenesis Regulation Of Transcription By RNA Polymerase II Segment Specification Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of paraxial mesoderm Somitogenesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699)	Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Malaria ( 31844061) Severe autoimmune type 2 diabetes ( 34737425)
Interacting Genes		28 interacting genes: AP1B1 ATP11B BRAT1 CCDC172 CTAG1A CTAG1B DNALI1 EXOC7 FERD3L HAP1 ID1 ID2 ID3 IGFBP6 ITGB3BP LDOC1 MAGEA6 MYF5 MYL9 NECAB2 OST4 SERTAD3 TEPSIN TEX12 TRAF1 TTC23L ZMYND12 ZWINT	20 interacting genes: CATSPERT DCTN2 FAM13C FAM161B HDDC3 ISCU KDM1A MRPL11 MSGN1 NEFL PCDHB12 PLEKHF2 PRKAA2 PSTPIP1 SH2D4A SMARCE1 TCHP TEAD4 TXNDC9 VPS9D1
Entrez ID		343930	374355
HPRD ID			18604
Ensembl ID		ENSG00000151379	ENSG00000182645
Uniprot IDs		A6NI15	P0C7W6
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Transcription Regulator Inhibitor Activity Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-binding Transcription Factor Activity Regulation Of Dopaminergic Neuron Differentiation Regulation Of DNA-binding Transcription Factor Activity
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