DPP7 and CSF2

		DPP7	CSF2
Description		dipeptidyl peptidase 7	colony stimulating factor 2
Image
GO Annotations	Cellular Component	Extracellular Region Lysosome Golgi Apparatus Cytoplasmic Vesicle Vesicle Azurophil Granule Lumen Extracellular Exosome	Extracellular Region Extracellular Space Plasma Membrane Granulocyte Macrophage Colony-stimulating Factor Receptor Complex
	Molecular Function	Aminopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Dipeptidyl-peptidase Activity Hydrolase Activity Serine-type Exopeptidase Activity	Cytokine Activity Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Proteolysis Lysosomal Protein Catabolic Process	Histamine Secretion Embryonic Placenta Development Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Via JAK-STAT Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Regulation Of Signal Transduction Regulation Of Gene Expression Positive Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Myeloid Cell Differentiation Neutrophil Differentiation Monocyte Differentiation Macrophage Differentiation Positive Regulation Of Cell Migration Positive Regulation Of Interleukin-23 Production Response To Silicon Dioxide Response To Fluid Shear Stress Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Epithelial Fluid Transport Regulation Of Cell Population Proliferation Myeloid Dendritic Cell Differentiation Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of DNA-templated Transcription Regulation Of Developmental Process Positive Regulation Of Leukocyte Proliferation Cellular Response To Lipopolysaccharide Positive Regulation Of Podosome Assembly Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Dendritic Cell Differentiation Cell Surface Receptor Signaling Pathway Via STAT Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Neutrophil degranulation	Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin-10 signaling RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Interleukin receptor SHC signaling
Drugs			KB002
Diseases
GWAS		Pursuit maintenance gain ( 29064472)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 23128233 28067908) Rheumatoid arthritis ( 22446963 24390342 30423114) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		5 interacting genes: CFTR CSF2 ERGIC1 NPHP3 XRN1	17 interacting genes: CSF2RA CSF2RB DPP7 ETF1 FBN2 IKBKE IL3RA KITLG MEOX2 P2RX7 PRG2 S100A6 S100P SDC2 SEMA7A TAGLN TREML2
Entrez ID		29952	1437
HPRD ID		07634	00734
Ensembl ID		ENSG00000176978	ENSG00000164400
Uniprot IDs		Q9UHL4	P04141
PDB IDs		3JYH 3N0T 4EBB	1CSG 2GMF 4NKQ 4RS1 5C7X 5D70 5D71 5D72 6BFQ 6BFS
Enriched GO Terms of Interacting Partners?		Epithelial Fluid Transport Fluid Transport Transepithelial Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Determination Of Stomach Left/right Asymmetry Determination Of Intestine Left/right Asymmetry Cellular Response To Puromycin Cellular Response To Cycloheximide Positive Regulation Of Anion Channel Activity Response To Purine-containing Compound Response To Lipid Positive Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Response To Silicon Dioxide Maintenance Of Animal Organ Identity Ciliary Inversin Compartment 5'-3' RNA Exonuclease Activity Cellular Response To Oxygen-containing Compound Transepithelial Water Transport Determination Of Pancreatic Left/right Asymmetry Response To Cycloheximide Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Response To Ketone Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Positive Regulation Of Interleukin-23 Production Histamine Secretion Ureter Development Determination Of Digestive Tract Left/right Asymmetry Convergent Extension Involved In Gastrulation Determination Of Liver Left/right Asymmetry Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Response To Alcohol Neutrophil Differentiation G-quadruplex RNA Binding Amelogenesis Histamine Transport Atrial Septum Development G-quadruplex DNA Binding ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Interleukin-23 Production 5'-3' Exonuclease Activity	Interleukin-3 Receptor Activity Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Regulation Of Macrophage Cytokine Production Cytokine Receptor Activity External Side Of Plasma Membrane Interleukin-3-mediated Signaling Pathway Cellular Response To Interleukin-3 Extracellular Matrix Signaling Receptor Activity Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of Macrophage Cytokine Production Cytokine-mediated Signaling Pathway Positive Regulation Of Leukocyte Proliferation Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response Cytokine Binding Positive Regulation Of Bone Mineralization Translation Termination Factor Activity Cytoplasmic Translational Termination Regulation Of Production Of Molecular Mediator Of Immune Response Leukocyte Apoptotic Process Positive Regulation Of Biomineral Tissue Development Immune System Process Positive Regulation Of Ossification Neural Crest Cell Migration Mesenchymal Cell Migration Positive Regulation Of Cytokine Production Positive Regulation Of Cell Population Proliferation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?