GTF3C1 and DEDD

Number of citations of the paper that reports this interaction (PubMedID 11965497)
0

Data Source:
HPRD (two hybrid, in vitro)

		GTF3C1	DEDD
Description		general transcription factor IIIC subunit 1	death effector domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex	Nucleus Nucleolus Cytoplasm
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter RRNA Transcription TRNA Transcription 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III	Developmental Process Involved In Reproduction Apoptotic Process Spermatogenesis Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Protein Catabolic Process Regulation Of Apoptotic Process Decidualization Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Asthma ( 31959851) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		25 interacting genes: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 PRPF38A RBM23 SNU13 SUMO2 SUPT5H TBC1D17 UBC UBE3A WEE2-AS1	24 interacting genes: APLP2 APP BATF2 CASP10 CASP3 CASP8 CFLAR DEDD2 FADD GTF3C1 GTF3C3 HOXD4 IRF9 KRT18 KRT8 MPZ NR1I3 PRRC2C SDHC SHMT1 SLC19A2 SMAD3 UAP1 VPS26A
Entrez ID		2975	9191
HPRD ID		07540	06022
Ensembl ID		ENSG00000077235	ENSG00000158796
Uniprot IDs		Q12789	B1AQP5 O75618
PDB IDs		8CLI 8CLJ 8CLK 8CLL
Enriched GO Terms of Interacting Partners?		Regulation Of Circadian Rhythm	Ripoptosome CD95 Death-inducing Signaling Complex Death-inducing Signaling Complex Extrinsic Apoptotic Signaling Pathway Death Receptor Binding Apoptotic Signaling Pathway Death Effector Domain Binding Positive Regulation Of Neuron Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Cysteine-type Endopeptidase Activity Positive Regulation Of Execution Phase Of Apoptosis Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Necroptotic Process Regulation Of Programmed Necrotic Cell Death Regulation Of Neuron Apoptotic Process Response To Anesthetic Transcription Factor TFIIIC Complex 5S Class RRNA Transcription By RNA Polymerase III Cysteine-type Peptidase Activity Response To External Biotic Stimulus Epithelial Cell Apoptotic Process Positive Regulation Of Pyroptotic Inflammatory Response TRAIL-activated Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Response To Cobalt Ion Positive Regulation Of Interleukin-1 Beta Production Regulation Of Programmed Cell Death TRNA Transcription By RNA Polymerase III TRNA Transcription RNA Polymerase III General Transcription Initiation Factor Activity Scaffold Protein Binding Positive Regulation Of Interleukin-1 Production Cell Surface Receptor Signaling Pathway Cell Body Positive Regulation Of Macrophage Differentiation Hepatocyte Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction DNA Binding Transition Metal Ion Binding Platelet Alpha Granule Negative Regulation Of Necroptotic Process Regulation Of Interleukin-1 Beta Production Myeloid Cell Differentiation
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