WEE2-AS1 and CSTF1

Number of citations of the paper that reports this interaction (PubMedID 36168628)
47

Data Source:
BioGRID (unspecified method)

		WEE2-AS1	CSTF1
Description		WEE2 antisense RNA 1	cleavage stimulation factor subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP	Nucleus Nucleoplasm MRNA Cleavage Stimulating Factor Complex
	Molecular Function	Pre-mRNA 5'-splice Site Binding	RNA Binding Protein Binding
	Biological Process	MRNA 5'-splice Site Recognition	MRNA Processing MRNA 3'-end Processing
Pathways			mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Cognitive decline (age-related) ( 28078323)
Interacting Genes		161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1	12 interacting genes: BARD1 BRCA1 CSTF3 H2AC20 MIR140 MIR206 MIR92A2 MIRLET7A3 MIRLET7I POLR2A VCP WEE2-AS1
Entrez ID		285962	1477
HPRD ID		08286	02653
Ensembl ID		ENSG00000228775	ENSG00000101138
Uniprot IDs			Q05048
PDB IDs			6B3X
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex BRCA1-B Complex Negative Regulation Of Gene Expression Nuclear Ubiquitin Ligase Complex BRCA1-C Complex MRNA Base-pairing Post-transcriptional Repressor Activity BRCA1-A Complex Ubiquitin-modified Histone Reader Activity Post-transcriptional Regulation Of Gene Expression DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Regulation Of DNA Damage Checkpoint Negative Regulation Of Metabolic Process Protein K6-linked Ubiquitination Negative Regulation Of Macromolecule Biosynthetic Process Postreplication Repair Homologous Recombination Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Metabolic Process Positive Regulation Of Catabolic Process Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Interleukin-6 Production Mitotic G2/M Transition Checkpoint Negative Regulation Of MRNA 3'-end Processing Flavin Adenine Dinucleotide Catabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Lipid Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Ubiquitin Protein Ligase Binding Negative Regulation Of Cell Cycle G2/M Phase Transition Cellular Response To Ionizing Radiation Regulation Of MRNA Metabolic Process MRNA Cleavage Stimulating Factor Complex VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Intracellular Signal Transduction RNA-directed RNA Polymerase Activity
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