WEE2-AS1 and NISCH

Number of citations of the paper that reports this interaction (PubMedID 36168628)
47

Data Source:
BioGRID (unspecified method)

		WEE2-AS1	NISCH
Description		WEE2 antisense RNA 1	nischarin
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP	Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Intercellular Bridge Recycling Endosome
	Molecular Function	Pre-mRNA 5'-splice Site Binding	Integrin Binding Protein Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	MRNA 5'-splice Site Recognition	Apoptotic Process Rac Protein Signal Transduction Actin Cytoskeleton Organization Negative Regulation Of Cell Migration
Pathways			RAC1 GTPase cycle RND3 GTPase cycle RND2 GTPase cycle
Drugs			Tizanidine Agmatine Moxonidine Tepotinib
Diseases
GWAS			A body shape index ( 34021172) Apolipoprotein B levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Colon cancer ( 33632709) Distal colorectal cancer ( 33632709) General cognitive ability ( 29844566) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Parkinson's disease ( 28892059) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Schizophrenia ( 29483656 25056061 23974872) Triglyceride levels ( 32203549) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-hip ratio ( 20935629) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1	11 interacting genes: AR BTG3 CLIC6 IRS4 ITGA5 KLHL20 OGT PTGER4 TWF2 VHL WEE2-AS1
Entrez ID		285962	11188
HPRD ID		08286	11391
Ensembl ID		ENSG00000228775	ENSG00000010322
Uniprot IDs			C9J715 Q9Y2I1
PDB IDs			3P0C 8ESF
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization	Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Prostate Induction Regulation Of Programmed Cell Death Male Genitalia Morphogenesis POU Domain Binding Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Developmental Process Negative Regulation Of Apoptotic Process Cellular Response To Oxygen-containing Compound Male Somatic Sex Determination Positive Regulation Of Integrin Biosynthetic Process Integrin Alpha5-beta1 Complex Alphav-beta3 Integrin-vitronectin Complex Negative Regulation Of Eosinophil Extravasation Negative Regulation Of Integrin Activation Negative Regulation Of Eosinophil Migration Regulation Of Protein-containing Complex Assembly Negative Regulation Of Protein-containing Complex Assembly Prostaglandin Receptor Activity Ubiquitin-like Ligase-substrate Adaptor Activity Regulation Of TORC1 Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein O-acetylglucosaminyltransferase Activity Protein K33-linked Ubiquitination Type II Interferon Binding D2 Dopamine Receptor Binding D4 Dopamine Receptor Binding D3 Dopamine Receptor Binding Pre-mRNA 5'-splice Site Binding
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