VSTM1 and MRM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VSTM1	MRM1
Description		V-set and transmembrane domain containing 1	mitochondrial rRNA methyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Cytokine Activity Protein Binding	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity RRNA (guanosine-2'-O-)-methyltransferase Activity
	Biological Process	Immune System Process Immune Response-regulating Signaling Pathway	RRNA Modification RRNA 2'-O-methylation RRNA Processing RNA Processing RRNA Methylation Methylation
Pathways			rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Small cell lung carcinoma ( 28604730)	Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)
Interacting Genes		29 interacting genes: ADGRG3 APH1B AQP6 ARL13B CD53 CLDN7 CLDN9 CLEC10A COQ9 ERGIC3 FAM209A FATE1 FBXO2 FCGR1A FNDC9 GJB5 GOLM1 GPX8 HCST KCNJ6 LAMP1 LMNA LRRC4C MANSC1 MRM1 PLPP2 SLC60A2 STMN4 TMEM248	43 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 GSDMB ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1
Entrez ID		284415	79922
HPRD ID		15615	08656
Ensembl ID		ENSG00000189068	ENSG00000278619
Uniprot IDs		D2DJS5 D2DJS6 Q6UX27	Q6IN84
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Polyol Transmembrane Transport Renal Water Transport Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Water Channel Activity Glycerol Transmembrane Transporter Activity Membrane Renal Water Homeostasis Cellular Response To Mercury Ion Water Transport Multicellular Organismal-level Water Homeostasis Water Transmembrane Transporter Activity Renal Water Absorption Fluid Transport Channel Activity Cytokine Activity Response To Mercury Ion Response To Bacterium Positive Regulation Of Monocyte Chemotactic Protein-1 Production
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