MRM1 and RNASE10

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRM1	RNASE10
Description		mitochondrial rRNA methyltransferase 1	ribonuclease A family member 10 (inactive)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Extracellular Region
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity RRNA (guanosine-2'-O-)-methyltransferase Activity	Nucleic Acid Binding RNA Nuclease Activity Protein Binding
	Biological Process	RRNA Modification RRNA 2'-O-methylation RRNA Processing RNA Processing RRNA Methylation Methylation	Cell Adhesion Single Fertilization Positive Regulation Of Cell-cell Adhesion Heterotypic Cell-cell Adhesion Defense Response To Gram-positive Bacterium Regulation Of Fertilization Positive Regulation Of Flagellated Sperm Motility
Pathways		rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)	Immune response to measles-mumps-rubella vaccine ( 24811271)
Interacting Genes		43 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 GSDMB ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1	6 interacting genes: BFSP2 CREB3L1 MRM1 SGPL1 SGTA SGTB
Entrez ID		79922	338879
HPRD ID		08656	18495
Ensembl ID		ENSG00000278619	ENSG00000182545
Uniprot IDs		Q6IN84	Q5GAN6 W0UTC4
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyol Transmembrane Transport Renal Water Transport Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Water Channel Activity Glycerol Transmembrane Transporter Activity Membrane Renal Water Homeostasis Cellular Response To Mercury Ion Water Transport Multicellular Organismal-level Water Homeostasis Water Transmembrane Transporter Activity Renal Water Absorption Fluid Transport Channel Activity Cytokine Activity Response To Mercury Ion Response To Bacterium Positive Regulation Of Monocyte Chemotactic Protein-1 Production	TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Negative Regulation Of Response To Endoplasmic Reticulum Stress Protein Targeting To Membrane Sphinganine-1-phosphate Aldolase Activity Regulation Of Response To Endoplasmic Reticulum Stress RRNA (guanosine-2'-O-)-methyltransferase Activity RRNA (guanine) Methyltransferase Activity RRNA 2'-O-methylation Extracellular Matrix Constituent Secretion BAT3 Complex Binding Molecular Adaptor Activity Establishment Of Protein Localization To Membrane Protein Targeting Negative Regulation Of ERAD Pathway Response To Endoplasmic Reticulum Stress Lens Fiber Cell Development Luteinization Carbon-carbon Lyase Activity
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