MRM1 and NRM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MRM1	NRM
Description		mitochondrial rRNA methyltransferase 1	nurim
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix	Nucleus Nuclear Envelope Nuclear Inner Membrane Membrane Nuclear Membrane
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity RRNA (guanine) Methyltransferase Activity Transferase Activity RRNA (guanosine-2'-O-)-methyltransferase Activity	Protein Binding
	Biological Process	RRNA Modification RRNA 2'-O-methylation RRNA Processing RNA Processing RRNA Methylation Methylation
Pathways		rRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)	Alcohol dependence symptom count ( 27151647) Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31217584) Itch intensity from mosquito bite ( 28199695) Number of sexual partners ( 30643258)
Interacting Genes		43 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 GSDMB ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1	51 interacting genes: AGR3 ANK1 AQP6 ARL13B ATP6V0B BIK CLRN1 CNR2 CPLX4 CREB3L1 CYB5R3 CYBC1 ERGIC3 ERP29 FAM209A FCER1G FFAR2 FRMD3 GOLT1A GORAB GPR151 GPR42 GPX8 HDAC11 HHLA2 HSD17B13 KIR2DL3 MFF MGST3 MRM1 OPN1LW PARP15 PEX12 RETREG3 RHBDD2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A2 SLC10A6 SLC18A1 SLC30A2 SLC35H1 SPAG4 SSMEM1 STX1A SUN2 TMEM52B TMX2 TRIM59
Entrez ID		79922	11270
HPRD ID		08656	10120
Ensembl ID		ENSG00000278619	ENSG00000137404
Uniprot IDs		Q6IN84	A0A1U9X845 B3KQU6 Q8IXM6
PDB IDs
Enriched GO Terms of Interacting Partners?		Polyol Transmembrane Transport Renal Water Transport Glycerol Transmembrane Transport Carbohydrate Transport Carbohydrate Transmembrane Transport Water Channel Activity Glycerol Transmembrane Transporter Activity Membrane Renal Water Homeostasis Cellular Response To Mercury Ion Water Transport Multicellular Organismal-level Water Homeostasis Water Transmembrane Transporter Activity Renal Water Absorption Fluid Transport Channel Activity Cytokine Activity Response To Mercury Ion Response To Bacterium Positive Regulation Of Monocyte Chemotactic Protein-1 Production	Membrane Protein Binding Endoplasmic Reticulum Bile Acid:sodium Symporter Activity
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