APOBEC3C and SUN2

		APOBEC3C	SUN2
Description		apolipoprotein B mRNA editing enzyme catalytic subunit 3C	Sad1 and UNC84 domain containing 2
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GO Annotations	Cellular Component	P-body Nucleus Cytoplasm	Chromosome, Telomeric Region Condensed Nuclear Chromosome Nucleus Nuclear Envelope Nuclear Inner Membrane Endosome Endosome Membrane Membrane Nuclear Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	RNA Binding Catalytic Activity Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding	Protein Binding Lamin Binding Microtubule Binding Identical Protein Binding Protein-membrane Adaptor Activity Cytoskeleton-nuclear Membrane Anchor Activity
	Biological Process	Immune System Process Transposable Element Silencing Negative Regulation Of Macromolecule Biosynthetic Process Cytidine To Uridine Editing Positive Regulation Of Gene Expression Via Chromosomal CpG Island Demethylation Clearance Of Foreign Intracellular DNA Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination Defense Response To Symbiont	Mitotic Spindle Organization Nuclear Migration Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Positive Regulation Of Cell Migration Nuclear Migration Along Microfilament Meiotic Cell Cycle Centrosome Localization Nuclear Matrix Anchoring At Nuclear Membrane
Pathways		mRNA Editing: C to U Conversion Formation of the Editosome	Meiotic synapsis
Drugs
Diseases
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)	Heel bone mineral density ( 28869591) Prostate cancer ( 31562322) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		32 interacting genes: ARIH2 CHTOP CUL5 FBXO7 HHEX HNRNPK MYO10 NXF1 PCBP2 PCBP3 PRPF31 PRR3 RBM7 RBMX RBMY1A1 RBMY1F RBMY1J SF1 SHBG SNRPA SNW1 SRPK2 STK4 SUN2 TRAF3 TRIB3 UBC UNKL ZNF250 ZNF408 ZNF48 ZNF581	16 interacting genes: ALS2 APOBEC3C HGS MAFF MUC16 NRM PAEP PRPF6 PSMC2 RAB5B RASD2 RGS2 RPS20 SH3BP1 SRSF10 TXN2
Entrez ID		27350	25777
HPRD ID		09671	15611
Ensembl ID		ENSG00000244509	ENSG00000100242
Uniprot IDs		Q9NRW3	B0QY60 B0QY64 B4E2A6 Q9UH99
PDB IDs		3VM8 3VOW	3UNP 4DXR 4DXS 4DXT 4FI9 6WMD 6WME 6WMF 6WMG
Enriched GO Terms of Interacting Partners?		Spliceosomal Complex MRNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing RNA Binding RNA Splicing Regulation Of RNA Splicing Positive Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding MRNA Processing Nucleus Positive Regulation Of RNA Splicing RNA Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of MRNA Metabolic Process Identical Protein Binding Nucleoplasm Ubiquitin Protein Ligase Binding Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Ribonucleoprotein Complex Viral RNA Genome Replication Nucleobase-containing Compound Metabolic Process Transcription Export Complex Regulation Of Primary Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Cul5-RING Ubiquitin Ligase Complex Negative Regulation Of CGAS/STING Signaling Pathway Protein Binding Regulation Of Gene Expression Catalytic Step 2 Spliceosome Viral Genome Replication Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Protein K48-linked Ubiquitination Nuclear Speck Ubiquitin Ligase Complex Negative Regulation Of RNA Splicing Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process CGAS/STING Signaling Pathway Ubiquitin-protein Transferase Activity Nucleolus 14-3-3 Protein Binding	Endosome Organization Spliceosomal Tri-snRNP Complex Assembly
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