GLE1 and KRT10

Number of citations of the paper that reports this interaction (PubMedID 14645504)
0

Data Source:
BioGRID (two hybrid)

		GLE1	KRT10
Description		GLE1 RNA export mediator	keratin 10
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Ciliary Basal Body Nuclear Pore Cytoplasmic Filaments	Cornified Envelope Extracellular Region Extracellular Space Nucleus Cytoplasm Cytosol Cytoskeleton Intermediate Filament Cell Surface Membrane Keratin Filament Extracellular Exosome
	Molecular Function	Inositol Hexakisphosphate Binding Protein Binding Phospholipid Binding Translation Initiation Factor Binding Identical Protein Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis Protein Heterodimerization Activity
	Biological Process	MRNA Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport	Morphogenesis Of An Epithelium Peptide Cross-linking Keratinocyte Differentiation Intermediate Filament Organization Positive Regulation Of Epidermis Development Protein Heterotetramerization
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs			Zinc Copper Zinc acetate
Diseases		Lethal arthrogryposis with anterior horn cell disease Lethal congenital contractural syndrome (LCCS)	Epidermolytic hyperkeratosis (EHK); Bullous congenital ichthyosiform erythroderma (BCIE) Ichthyosis with confetti; Congenital reticular ichthyosiform erythroderma; Ichthyosis variegata
GWAS		Axial length ( 24144296) Body mass index ( 26426971)	Glucose homeostasis traits ( 25524916)
Interacting Genes		6 interacting genes: GOLGA2 KRT10 NUP155 NUP42 SYNE2 UXT	10 interacting genes: AKT1 ESR1 EVPL GLE1 OGT PRKCZ RNF26 SIRPA SMAD3 SNAPIN
Entrez ID		2733	3858
HPRD ID		04536	01021
Ensembl ID		ENSG00000119392	ENSG00000186395
Uniprot IDs		A0A804HJ70 B3KMG0 Q53GS7	A0A1B0GVI3 P13645
PDB IDs		6B4F 6B4I 6B4J	3ASW 4F1Z 4ZRY 6E2J 6EC0 6UUI
Enriched GO Terms of Interacting Partners?		Intracellular Transport Cellular Localization Establishment Of Localization In Cell Nuclear Envelope Nuclear Membrane Centrosome Cycle Microtubule Organizing Center Organization Organelle Transport Along Microtubule Nuclear Pore Protein Tetramerization Cytoskeleton Nuclear Pore Inner Ring Protein Localization To Nuclear Inner Membrane RNA Transport MRNA Transport Nuclear Export Nuclear Migration Along Microfilament Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Spindle Pole Positive Regulation Of Protein Glycosylation Transport Along Microtubule Nuclear Migration Along Microtubule Cytoskeleton-nuclear Membrane Anchor Activity Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Golgi Disassembly Nucleobase-containing Compound Transport Regulation Of Protein Glycosylation Microtubule-based Transport Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Cytoskeleton Organization Golgi Ribbon Formation Microtubule Binding Protein Complex Oligomerization Importin-alpha Family Protein Binding Establishment Of Organelle Localization Nuclear Transport Nucleocytoplasmic Transport Atrial Cardiac Muscle Cell Action Potential Meiotic Nuclear Membrane Microtubule Tethering Complex Golgi Cis Cisterna RPAP3/R2TP/prefoldin-like Complex Nuclear Export Signal Receptor Activity Protein Transport Asymmetric Cell Division Protein Localization To Nuclear Envelope Meiotic Spindle Assembly Protein Heterotetramerization Organelle Organization Positive Regulation Of Glycoprotein Biosynthetic Process	Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Defense Response Cellular Response To Oxygen-containing Compound Nitric-oxide Synthase Regulator Activity Intracellular Protein Localization Response To Hormone Response To Peptide Hormone Ciliary Basal Body Negative Regulation Of Cellular Component Organization Regulation Of Immune System Process Regulation Of Immune Response Response To Insulin Negative Regulation Of MiRNA Transcription Organelle Organization Positive Regulation Of Cell Adhesion Regulation Of Cellular Localization Maternal Process Involved In Female Pregnancy 14-3-3 Protein Binding Carbohydrate Homeostasis Glucose Homeostasis Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Gene Expression Phosphatidylinositol-3,4,5-trisphosphate Binding Protein K11-linked Ubiquitination Protein Metabolic Process Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Regulation Of Multicellular Organismal Process Regulation Of Intracellular Signal Transduction Transcription Corepressor Binding Positive Regulation Of T Cell Activation Transcription Coactivator Binding Positive Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Defense Response Regulation Of TRNA Methylation Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Late Endosome To Lysosome Transport Cellular Response To Glucose Stimulus TORC1 Signaling Negative Regulation Of Signal Transduction Apoptotic Mitochondrial Changes Positive Regulation Of TORC1 Signaling Protein Maturation Regulation Of Cell Adhesion
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