GLE1

Description		GLE1 RNA export mediator
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GO Annotations	Cellular Component	Extracellular Space Nucleus Nuclear Envelope Nuclear Pore Nucleolus Cytoplasm Centrosome Centriole Cytosol Membrane Nuclear Membrane Ciliary Basal Body Nuclear Pore Cytoplasmic Filaments
	Molecular Function	Inositol Hexakisphosphate Binding Protein Binding Phospholipid Binding Translation Initiation Factor Binding Identical Protein Binding
	Biological Process	MRNA Export From Nucleus Nucleocytoplasmic Transport Protein Transport Poly(A)+ MRNA Export From Nucleus MRNA Transport
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript
Drugs
Diseases		Lethal arthrogryposis with anterior horn cell disease Lethal congenital contractural syndrome (LCCS)
GWAS		Axial length ( 24144296) Body mass index ( 26426971)
Novel Interacting Genes		6 novel interacting genes: GOLGA2 KRT10 NUP155 NUP42 SYNE2 UXT
Interacting Genes		6 interacting genes: GOLGA2 KRT10 NUP155 NUP42 SYNE2 UXT
Entrez ID		2733
HPRD ID		04536
Ensembl ID		ENSG00000119392
Uniprot IDs		A0A804HJ70 B3KMG0 Q53GS7
PDB IDs		6B4F 6B4I 6B4J
Enriched GO Terms of Interacting Partners?		Intracellular Transport Cellular Localization Establishment Of Localization In Cell Nuclear Envelope Nuclear Membrane Centrosome Cycle Microtubule Organizing Center Organization Organelle Transport Along Microtubule Nuclear Pore Protein Tetramerization Cytoskeleton Nuclear Pore Inner Ring Protein Localization To Nuclear Inner Membrane RNA Transport MRNA Transport Nuclear Export Nuclear Migration Along Microfilament Nucleokinesis Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Spindle Pole Positive Regulation Of Protein Glycosylation Transport Along Microtubule Nuclear Migration Along Microtubule Cytoskeleton-nuclear Membrane Anchor Activity Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Golgi Disassembly Nucleobase-containing Compound Transport Regulation Of Protein Glycosylation Microtubule-based Transport Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Cytoskeleton Organization Golgi Ribbon Formation Microtubule Binding Protein Complex Oligomerization Importin-alpha Family Protein Binding Establishment Of Organelle Localization Nuclear Transport Nucleocytoplasmic Transport Atrial Cardiac Muscle Cell Action Potential Meiotic Nuclear Membrane Microtubule Tethering Complex Golgi Cis Cisterna RPAP3/R2TP/prefoldin-like Complex Nuclear Export Signal Receptor Activity Protein Transport Asymmetric Cell Division Protein Localization To Nuclear Envelope Meiotic Spindle Assembly Protein Heterotetramerization Organelle Organization Positive Regulation Of Glycoprotein Biosynthetic Process
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