NFU1 and RHBDD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NFU1	RHBDD2
Description		NFU1 iron-sulfur cluster scaffold	rhomboid domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Iron Ion Binding Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding	Serine-type Endopeptidase Activity Signal Recognition Particle Binding Protein Binding
	Biological Process	Iron-sulfur Cluster Assembly Protein Maturation	Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway
Pathways		Protein lipoylation
Drugs
Diseases
GWAS			Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		23 interacting genes: AGTRAP APOC1 APOC2 APOC4 CALCOCO2 CIDEB CMTM5 COIL DESI2 EPM2A FKBP7 HIRA HSPB1 MDK MORN3 NOA1 RHBDD2 SDCBP2 SH3BP4 TFIP11 TRIM23 ZNF688 ZSCAN5A	60 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NEDD4 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SLC71A3P SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30 YAP1
Entrez ID		27247	57414
HPRD ID		12163	11492
Ensembl ID		ENSG00000169599	ENSG00000005486
Uniprot IDs		Q9UMS0	Q6NTF9
PDB IDs		2LTM 2M5O
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Positive Regulation Of Autophagy Very-low-density Lipoprotein Particle Assembly Regulation Of Autophagy Chylomicron Phospholipid Efflux Negative Regulation Of Lipoprotein Particle Clearance Identical Protein Binding Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Clearance Lipid Transport Cholesterol Efflux Positive Regulation Of Catabolic Process Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Lipid Storage Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Negative Regulation Of Protein Kinase C Signaling Defecation HIR Complex Negative Regulation Of Hydrolase Activity Carbohydrate Phosphatase Activity Lipid Homeostasis Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Spliceosomal Complex Disassembly	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Synaptic Transmission, Dopaminergic Mitochondrial Envelope Mitochondrion Organization Apoptotic Signaling Pathway Response To Amphetamine Dopamine Metabolic Process Response To Alkaloid Regulation Of Catecholamine Secretion Protein Binding Response To Amine Membrane Epithelial Cell Proliferation Mitochondrial Membrane Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway Mitochondrial Matrix Catecholamine Catabolic Process Catecholamine Metabolic Process Dopamine Catabolic Process Protein Localization To Mitochondrion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?