RHBDD2 and TEX44

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHBDD2	TEX44
Description		rhomboid domain containing 2	testis expressed 44
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Membrane Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	Serine-type Endopeptidase Activity Signal Recognition Particle Binding Protein Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum Unfolded Protein Response ERAD Pathway
Pathways
Drugs
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neutrophil percentage of granulocytes ( 27863252) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sum eosinophil basophil counts ( 27863252)	Femur bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		60 interacting genes: ABHD16A ACSF2 ADORA2A BCL2L1 BCL2L2 CCR9 CHRM4 CIAO2A CIDEB COL8A1 COMT DIABLO DRD2 DYNC1H1 ERBB2 FKBP8 FMO4 GAL3ST3 GCSH GDF5-AS1 H2BC3 H4C7 IFI27L1 IL32 LETMD1 LIG4 MAOB MICOS13 MIEF2 MLX MMRN2 MPC2 MRM1 MRPL35 MTERF3 MYG1 NAALAD2 NCBP2AS2 NEDD4 NFU1 NRM PBX3 PTAFR ROMO1 RSAD2 SCGB3A1 SDHD SLC25A2 SLC25A3 SLC71A3P SNPH SYT16 TEX44 THBD TIMM17B TPRG1 TSR1 TUFM USP30 YAP1	13 interacting genes: APOC1 APP C3orf33 CIDEB COX20 CPT1B DERL1 MICOS13 MPC2 RHBDD2 SYPL1 TIMM17B TMEM14B
Entrez ID		57414	165100
HPRD ID		11492	14602
Ensembl ID		ENSG00000005486	ENSG00000177673
Uniprot IDs		Q6NTF9	Q53QW1
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Synaptic Transmission, Dopaminergic Mitochondrial Envelope Mitochondrion Organization Apoptotic Signaling Pathway Response To Amphetamine Dopamine Metabolic Process Response To Alkaloid Regulation Of Catecholamine Secretion Protein Binding Response To Amine Membrane Epithelial Cell Proliferation Mitochondrial Membrane Bcl-2 Family Protein Complex Intrinsic Apoptotic Signaling Pathway Mitochondrial Matrix Catecholamine Catabolic Process Catecholamine Metabolic Process Dopamine Catabolic Process Protein Localization To Mitochondrion	Mitochondrial Inner Membrane Signal Recognition Particle Binding Very-low-density Lipoprotein Particle Assembly High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Plasma Lipoprotein Particle Assembly Intracellular Transport Membrane Mitochondrion Mitochondrial Transmembrane Transport Protein-lipid Complex Assembly Lipoprotein Metabolic Process Mitochondrial Transport Regulation Of Triglyceride Metabolic Process Negative Regulation Of Phosphatidylcholine Catabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Localization Establishment Of Localization In Cell Endoplasmic Reticulum Unfolded Protein Response Lipid Transport Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Pyruvate Import Into Mitochondria Derlin-1-VIMP Complex Regulation Of Phosphatidylcholine Catabolic Process PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Carnitine O-palmitoyltransferase Activity ERAD Pathway Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
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