TUBGCP4 and GLYCTK

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TUBGCP4	GLYCTK
Description		tubulin gamma complex component 4	glycerate kinase
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton Membrane Recycling Endosome	Cytoplasm Mitochondrion Golgi Apparatus Cytosol
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Nucleotide Binding Protein Binding ATP Binding Glycerate Kinase Activity Kinase Activity Transferase Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly	Protein Phosphorylation Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Fructose catabolism
Drugs
Diseases
GWAS		Glycine levels ( 30837465) HDL cholesterol ( 30275531) Liver enzyme levels (alkaline phosphatase) ( 33972514) Triglycerides ( 30275531)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972) Hemoglobin levels ( 32327693) Schizophrenia ( 23974872 28991256)
Interacting Genes		33 interacting genes: ADAMTSL4 ADD3 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM	59 interacting genes: ACTMAP ADAMTSL4 ANKRD53 ARMC5 ATP23 BAIAP2L2 CALCOCO2 CEP70 DTX2 EFHC2 GMPPB GOLGA2 IHO1 KLHL12 KRT13 KRT15 KRT19 KRT34 KRT75 KRTAP19-5 KRTAP6-2 KRTAP6-3 LZTS2 MAGED1 METTL15 METTL27 MGAT5B MIS18A MORN3 NFKBID NOTO NT5C2 PFDN5 PICK1 PLAGL2 POMC PRDM14 PUDP RBCK1 RBPMS REL SAXO1 SERTAD1 SMUG1 SNF8 SPAG8 SPRED1 STK33 TRIM27 TRIM42 TRIP13 TUBGCP4 UBP1 UFSP1 ZFP90 ZG16 ZIM2 ZNF620 ZNF688
Entrez ID		27229	132158
HPRD ID		10616	13586
Ensembl ID		ENSG00000137822	ENSG00000168237
Uniprot IDs		Q9UGJ1	C9JA32 Q8IVS8
PDB IDs		3RIP 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK
Enriched GO Terms of Interacting Partners?		Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Cytoskeleton Intermediate Filament Organization Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Identical Protein Binding Bergmann Glial Cell Differentiation Structural Constituent Of Skin Epidermis Scaffold Protein Binding Microtubule Astrocyte Development	Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Protein Binding Cytoskeleton Cytosol Axonemal Microtubule Supramolecular Fiber Organization Structural Molecule Activity
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