TUBGCP4 and SDSL

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		TUBGCP4	SDSL
Description		tubulin gamma complex component 4	serine dehydratase like
Image
GO Annotations	Cellular Component	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton Membrane Recycling Endosome	Cytosol
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	L-serine Ammonia-lyase Activity Threonine Deaminase Activity Glutamate Racemase Activity Lyase Activity Isomerase Activity Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle Protein-containing Complex Assembly	Amino Acid Metabolic Process L-serine Catabolic Process Lipid Metabolic Process
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Threonine catabolism Serine metabolism
Drugs			Pyridoxal phosphate
Diseases
GWAS		Glycine levels ( 30837465) HDL cholesterol ( 30275531) Liver enzyme levels (alkaline phosphatase) ( 33972514) Triglycerides ( 30275531)	Body mass index ( 26426971)
Interacting Genes		33 interacting genes: ADAMTSL4 ADD3 AP2B1 CBY2 CCDC85B CHIC2 DGCR6 EFHC2 FBF1 FDXACB1 GFAP GLYCTK GOLGA2 KCTD17 KRT15 KRT18 KRT4 KRT6B LZTR1 MAD1L1 NUDT3 PAK5 PHKA1 RNF146 RPRD1B SDSL STN1 TRIM27 TRIM55 TRIM63 TUBG1 USHBP1 VIM	1 interacting genes: TUBGCP4
Entrez ID		27229	113675
HPRD ID		10616	11542
Ensembl ID		ENSG00000137822	ENSG00000139410
Uniprot IDs		Q9UGJ1	Q96GA7
PDB IDs		3RIP 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK	2RKB
Enriched GO Terms of Interacting Partners?		Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Structural Constituent Of Cytoskeleton Intermediate Filament Organization Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Identical Protein Binding Bergmann Glial Cell Differentiation Structural Constituent Of Skin Epidermis Scaffold Protein Binding Microtubule Astrocyte Development	Microtubule Minus-end Binding Gamma-tubulin Ring Complex Gamma-tubulin Complex Microtubule Nucleation Gamma-tubulin Binding Cytoplasmic Microtubule Organization Structural Constituent Of Cytoskeleton Microtubule Organizing Center Spindle Assembly Meiotic Cell Cycle Spindle Organization Mitotic Cell Cycle Recycling Endosome Spindle Pole Microtubule Cytoskeleton Membraneless Organelle Assembly Microtubule
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