PRPF40B and TRAFD1

		PRPF40B	TRAFD1
Description		pre-mRNA processing factor 40B	TRAF-type zinc finger domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus U1 SnRNP Nuclear Matrix Nuclear Speck U2-type Prespliceosome	Mitochondrion
	Molecular Function	RNA Binding Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing MRNA Cis Splicing, Via Spliceosome	Negative Regulation Of Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)	Alanine aminotransferase levels ( 30718733) Alcohol consumption (max-drinks) ( 29460428) Alcohol dependence symptom count ( 29460428) Aspartate aminotransferase levels ( 30718733) Body mass index ( 25673413 26426971) Coffee consumption ( 29367735) Confectionary intake ( 33632354) Hemoglobin ( 19862010) Hemoglobin levels ( 32327693) Neutrophil count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 26394269) Response to alcohol consumption (flushing response) ( 29460428) Spleen volume ( 34128465) Systemic lupus erythematosus ( 28714469) Type 1 diabetes ( 17554300) White blood cell count ( 32888494)
Interacting Genes		6 interacting genes: FUBP1 HLA-DRA HTT MECP2 RNF10 TRAFD1	9 interacting genes: CFTR ESPL1 HTT KCNMB4 NGLY1 PRPF40B PTPRD TRAF6 UBC
Entrez ID		25766	10906
HPRD ID		11044	10994
Ensembl ID		ENSG00000110844	ENSG00000135148
Uniprot IDs		A0A8Z5ADK7 F8VU11 Q6NWY9	O14545
PDB IDs			2D9K
Enriched GO Terms of Interacting Partners?		Cognition Regulation Of Glial Cell Proliferation	Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Odontogenesis Of Dentin-containing Tooth Endosome Membrane Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Establishment Of Spindle Localization Establishment Of Mitotic Spindle Localization Spindle Localization Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity
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