EML2 and KLHDC2

		EML2	KLHDC2
Description		EMAP like 2	kelch domain containing 2
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GO Annotations	Cellular Component	Cytoplasm Spindle Cytoskeleton Microtubule Microtubule Associated Complex Mitotic Spindle	Nucleus Nucleoplasm Nuclear Body Cullin-RING Ubiquitin Ligase Complex Cul2-RING Ubiquitin Ligase Complex Nuclear Membrane
	Molecular Function	Protein Binding Microtubule Binding Tubulin Binding	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Microtubule Cytoskeleton Organization Visual Perception Sensory Perception Of Sound Regulation Of Microtubule Nucleation Negative Regulation Of Microtubule Polymerization	Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
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Diseases
GWAS		Fruit consumption ( 32066663) Hemoglobin A1c levels ( 29403010) Subcutaneous adipose tissue ( 22589738) Type 2 diabetes ( 32499647)
Interacting Genes		13 interacting genes: BPIFA1 EIF3F EXD1 IFI35 IFT88 KLHDC2 PLEKHF2 PTTG2 REL RFC5 SNX32 SPANXA1 SPANXA2	12 interacting genes: ATL1 EML2 ERO1A EZH2 MIS12 NEDD8 RBX1 RIC8B SELENOK SELENOS STRN4 USP1
Entrez ID		24139	23588
HPRD ID		16860	08824
Ensembl ID		ENSG00000125746	ENSG00000165516
Uniprot IDs		O95834	Q9Y2U9
PDB IDs		4CGB	6DO3 6DO4 6DO5 8EBL 8EBM 8EBN 8PIF 8SGE 8SGF 8SH2 8UXS 9BC9 9BCA 9BCC
Enriched GO Terms of Interacting Partners?			Response To Oxidative Stress Protein Modification Process Hepatocyte Homeostasis Cellular Response To Stress Cellular Response To Oxidative Stress Protein Neddylation Positive Regulation Of Error-prone Translesion Synthesis Cell Redox Homeostasis Response To Endoplasmic Reticulum Stress Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Subcompartment Cellular Response To Chemical Stress
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