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KLHDC2
Description
kelch domain containing 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nuclear Body
Cullin-RING Ubiquitin Ligase Complex
Cul2-RING Ubiquitin Ligase Complex
Nuclear Membrane
Molecular Function
Protein Binding
Ubiquitin-like Ligase-substrate Adaptor Activity
Biological Process
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes
12 novel interacting genes:
ATL1
EML2
ERO1A
EZH2
MIS12
NEDD8
RBX1
RIC8B
SELENOK
SELENOS
STRN4
USP1
Interacting Genes
12 interacting genes:
ATL1
EML2
ERO1A
EZH2
MIS12
NEDD8
RBX1
RIC8B
SELENOK
SELENOS
STRN4
USP1
Entrez ID
23588
HPRD ID
08824
Ensembl ID
ENSG00000165516
Uniprot IDs
Q9Y2U9
PDB IDs
6DO3
6DO4
6DO5
8EBL
8EBM
8EBN
8PIF
8SGE
8SGF
8SH2
8UXS
9BC9
9BCA
9BCC
Enriched GO Terms of Interacting Partners
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Response To Oxidative Stress
Protein Modification Process
Hepatocyte Homeostasis
Cellular Response To Stress
Cellular Response To Oxidative Stress
Protein Neddylation
Positive Regulation Of Error-prone Translesion Synthesis
Cell Redox Homeostasis
Response To Endoplasmic Reticulum Stress
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Endoplasmic Reticulum Subcompartment
Cellular Response To Chemical Stress
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