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KLHDC2

Description kelch domain containing 2
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Nuclear Body
  • Cullin-RING Ubiquitin Ligase Complex
  • Cul2-RING Ubiquitin Ligase Complex
  • Nuclear Membrane
Molecular Function
  • Protein Binding
  • Ubiquitin-like Ligase-substrate Adaptor Activity
Biological Process
  • Protein Ubiquitination
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes 12 novel interacting genes: ATL1 EML2 ERO1A EZH2 MIS12 NEDD8 RBX1 RIC8B SELENOK SELENOS STRN4 USP1
Interacting Genes 12 interacting genes: ATL1 EML2 ERO1A EZH2 MIS12 NEDD8 RBX1 RIC8B SELENOK SELENOS STRN4 USP1
Entrez ID 23588
HPRD ID 08824
Ensembl ID ENSG00000165516
Uniprot IDs Q9Y2U9
PDB IDs 6DO3 6DO4 6DO5 8EBL 8EBM 8EBN 8PIF 8SGE 8SGF 8SH2 8UXS 9BC9 9BCA 9BCC
Enriched GO Terms of Interacting Partners?
  • Response To Oxidative Stress
  • Protein Modification Process
  • Hepatocyte Homeostasis
  • Cellular Response To Stress
  • Cellular Response To Oxidative Stress
  • Protein Neddylation
  • Positive Regulation Of Error-prone Translesion Synthesis
  • Cell Redox Homeostasis
  • Response To Endoplasmic Reticulum Stress
  • Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
  • Endoplasmic Reticulum Subcompartment
  • Cellular Response To Chemical Stress
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