CTTN and ANKZF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		CTTN	ANKZF1
Description		cortactin	ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Podosome Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Actin Filament Plasma Membrane Clathrin-coated Pit Focal Adhesion Cell Cortex Voltage-gated Potassium Channel Complex Membrane Lamellipodium Cell Junction Endocytic Vesicle Dendrite Growth Cone Cortical Cytoskeleton Cell Projection Dendritic Spine Synapse Anchoring Junction Postsynapse Postsynaptic Actin Cytoskeleton Glutamatergic Synapse Mitotic Spindle Midzone	Cytoplasm Membrane
	Molecular Function	Protein Binding Profilin Binding Cadherin Binding Proline-rich Region Binding Arp2/3 Complex Binding	Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Binding Zinc Ion Binding Hydrolase Activity Metal Ion Binding Catalytic Activity, Acting On A TRNA
	Biological Process	Intracellular Protein Transport Endocytosis Receptor-mediated Endocytosis Substrate-dependent Cell Migration, Cell Extension Signal Transduction Actin Cytoskeleton Organization Regulation Of Axon Extension Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Smooth Muscle Contraction Focal Adhesion Assembly Neuron Projection Morphogenesis Cell Motility Positive Regulation Of Chemotaxis Regulation Of Cell Projection Assembly Dendritic Spine Maintenance Extrinsic Apoptotic Signaling Pathway Lamellipodium Organization Modification Of Postsynaptic Actin Cytoskeleton Modification Of Postsynaptic Structure Regulation Of Mitophagy Negative Regulation Of Extrinsic Apoptotic Signaling Pathway	TRNA 3'-terminal CCA Addition Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins ERAD Pathway TRNA 3'-end Processing Cellular Response To Hydrogen Peroxide Rescue Of Stalled Ribosome
Pathways		RHO GTPases activate PAKs Clathrin-mediated endocytosis	Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide
Drugs
Diseases
GWAS
Interacting Genes		59 interacting genes: ACD ACTA1 ACTG1 ACTR3 ANKZF1 ARHGAP17 ARHGAP8 ATM CASP3 CD2AP CD5 CHD3 CPSF7 CTNND1 CTNND2 CTTNBP2 DNM1 DNM2 EGFR FER FGD1 GRB2 GRIA2 GTSE1 HAX1 HIP1R KCNA2 KEAP1 MET MYLK NHSL2 NXF1 PRPF6 RBM15 RPL23A RPL37 RPL9 RSPH1 SDC3 SF1 SF3B4 SFPQ SH3BP2 SHANK2 SHANK3 SIRT1 SMURF1 SPRR2A SRC SYK TINF2 TJP1 TNK2 TRIM15 USP7 WASL WIPF1 YTHDF1 YTHDF3	10 interacting genes: APP AURKB CA2 CRK CTTN DNAJB11 NRSN2 STAT6 UBC YWHAE
Entrez ID		2017	55139
HPRD ID		01268	07673
Ensembl ID		ENSG00000085733	ENSG00000163516
Uniprot IDs		Q14247 Q53HG7	B8ZZS4 Q9H8Y5
PDB IDs		1X69 2D1X
Enriched GO Terms of Interacting Partners?		SH3 Domain Binding Cellular Component Assembly Cytoplasm Regulation Of Cellular Component Organization Anchoring Junction Lamellipodium Regulation Of Actin Cytoskeleton Organization Regulation Of Organelle Organization Actin Cytoskeleton Actin Filament Regulation Of Actin Filament-based Process Cytosol Organelle Organization Actin Filament Organization Regulation Of Actin Filament Organization Cellular Response To Chemical Stress Protein Tyrosine Kinase Activity Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Metabolic Process Negative Regulation Of Telomere Maintenance Actin Filament-based Process Regulation Of Cytoskeleton Organization Vesicle Scission Negative Regulation Of Membrane Tubulation Podosome Grb2-EGFR Complex Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of TOR Signaling Cell Projection Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Vesicle-mediated Transport Postsynapse Organization Response To Reactive Oxygen Species Regulation Of Chromosome Organization Positive Regulation Of Cellular Component Organization Cytoskeleton Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Postsynaptic Density Regulation Of Signal Transduction Actin Cytoskeleton Organization Dendritic Spine Morphogenesis Regulation Of Clathrin-dependent Endocytosis Response To Oxidative Stress Positive Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Telomere Maintenance Cellular Response To Reactive Oxygen Species Regulation Of Autophagy Regulation Of Supramolecular Fiber Organization	Response To Yeast Mitotic Spindle Midzone Regulation Of Immune Response Ephrin Receptor Binding Positive Regulation Of Supramolecular Fiber Organization Regulation Of Innate Immune Response Neuron Projection Organization Regulation Of Toll-like Receptor Signaling Pathway Response To Nerve Growth Factor Dendrite Development Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Immune Response Negative Regulation Of Immune System Process Regulation Of T Cell Migration Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Defense Response Growth Cone Lamellipodium Regulation Of Immune System Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Lymphocyte Migration Clathrin-coated Pit Response To Fungus Lipoprotein Particle Positive Regulation Of Protein Import Positive Regulation Of Dipeptide Transmembrane Transport Cyanamide Hydratase Activity Helper T Cell Diapedesis Cerebral Cortex Development Hippocampus Development Signaling Adaptor Activity Protein Phosphorylated Amino Acid Binding Ubiquitin Protein Ligase Binding Scaffold Protein Binding Response To Cholecystokinin Mammary Gland Morphogenesis Regulation Of Heart Rate By Hormone Mitotic Sister Chromatid Biorientation Repair Of Mitotic Kinetochore Microtubule Attachment Defect Positive Regulation Of Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore Regulation Of Supramolecular Fiber Organization PTB Domain Binding Signaling Receptor Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Intracellular Monoatomic Cation Homeostasis Regulation Of Monoatomic Ion Transport Enzyme Binding
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