EMD and BCLAF1

Number of citations of the paper that reports this interaction (PubMedID 15009215)
0

Data Source:
HPRD (in vitro, two hybrid)

		EMD	BCLAF1
Description		emerin	BCL2 associated transcription factor 1
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Cytosol Microtubule Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum TMEM240-body	Nucleus Nucleoplasm Cytoplasm Mediator Complex Nuclear Speck
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	DNA Binding Transcription Coregulator Activity RNA Binding Protein Binding
	Biological Process	Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid Fibril Formation	Apoptotic Process DNA Damage Response Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Leukemia Inhibitory Factor Positive Regulation Of DNA-templated Transcription Initiation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerization of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS		Mean spheric corpuscular volume ( 32888494)
Interacting Genes		100 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AQP6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SLC10A1 SLC35H1 SOWAHB SRC SSMEM1 STX1A SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAV1 WEE2-AS1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774	16 interacting genes: BCL2 BCL2L1 CEBPA CHD1 CLK1 CSNK2A1 EMD H19 LEMD3 OGT PIN1 RNF10 SRPK2 USP7 WEE2-AS1 YWHAG
Entrez ID		2010	9774
HPRD ID		02309	16544
Ensembl ID		ENSG00000102119	ENSG00000029363
Uniprot IDs		P50402	E9PK91 Q9NYF8
PDB IDs		1JEI 2ODC 2ODG 6GHD 6RPR 7NDY	7RJN 7RJR
Enriched GO Terms of Interacting Partners?		Protein Binding Inward Rectifier Potassium Channel Activity Fc-gamma Receptor Signaling Pathway	Dendritic Cell Apoptotic Process Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Negative Regulation Of Catabolic Process Negative Regulation Of Cell Communication Symbiont-mediated Disruption Of Host Cell PML Body Negative Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Protein Localization Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process BH3 Domain Binding Regulation Of Protein Stability Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Dendritic Cell Apoptotic Process Bcl-2 Family Protein Complex Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process TORC1 Signaling Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Intracellular Signal Transduction Nucleus Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Nutrient Levels Protein Stabilization TOR Signaling Cellular Response To Nutrient Levels Protein Localization To Vacuole Nuclear Membrane Regulation Of Cellular Localization Regulation Of TORC1 Signaling Negative Regulation Of Autophagy Regulation Of Translational Initiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Anoikis Negative Regulation Of Protein Metabolic Process Programmed Cell Death Involved In Cell Development Regulation Of Signal Transduction By P53 Class Mediator Sin3-type Complex Release Of Cytochrome C From Mitochondria Regulation Of Protein Metabolic Process Regulation Of Anoikis Regulation Of Cell Cycle Cellular Response To Stress Negative Regulation Of Proteolysis Regulation Of Autophagy Protein Modification Process Regulation Of Proteolysis
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