EMD and TMEM201

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		EMD	TMEM201
Description		emerin	transmembrane protein 201
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Cytosol Microtubule Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum TMEM240-body	Spindle Pole Nucleus Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum
	Molecular Function	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding	Protein Binding Lamin Binding Actin Filament Binding
	Biological Process	Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid Fibril Formation	Angiogenesis Nuclear Envelope Organization Nuclear Migration Positive Regulation Of Endothelial Cell Migration Fibroblast Migration Nuclear Migration Along Microtubule Centrosome Localization Protein Localization To Nuclear Envelope
Pathways		Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerization of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases		Emery-Dreifuss muscular dystrophy
GWAS		Mean spheric corpuscular volume ( 32888494)
Interacting Genes		100 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AQP6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SLC10A1 SLC35H1 SOWAHB SRC SSMEM1 STX1A SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAV1 WEE2-AS1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774	24 interacting genes: CLEC17A CPLX4 CYB5R3 DNAJC1 EMD FATE1 FRMD3 GOLM2 GPR152 KCNJ9 LHFPL5 LMNA LRRC25 MFF MINAR1 NDUFAF2 NPHP4 PTPN5 SLC26A6 TMEM237 TMEM35A TMX2 UBC VEZT
Entrez ID		2010	199953
HPRD ID		02309	17991
Ensembl ID		ENSG00000102119	ENSG00000188807
Uniprot IDs		P50402	Q5SNT2
PDB IDs		1JEI 2ODC 2ODG 6GHD 6RPR 7NDY
Enriched GO Terms of Interacting Partners?		Protein Binding Inward Rectifier Potassium Channel Activity Fc-gamma Receptor Signaling Pathway	Membrane Endoplasmic Reticulum Mitochondrial Outer Membrane
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