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DVL2 and DPPA2
Number of citations of the paper that reports this interaction (PubMedID
16189514
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
DVL2
DPPA2
Description
dishevelled segment polarity protein 2
developmental pluripotency associated 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Aggresome
Lateral Plasma Membrane
Nuclear Body
Clathrin-coated Vesicle
Cytoplasmic Vesicle
Apical Part Of Cell
Clathrin-coated Endocytic Vesicle
Nucleus
Nucleoplasm
Molecular Function
Frizzled Binding
Protein Binding
Protein Kinase Binding
Protein Domain Specific Binding
Protein-macromolecule Adaptor Activity
Small GTPase Binding
Identical Protein Binding
Chromatin Binding
Protein Binding
Biological Process
Neural Tube Closure
Heart Looping
Heart Morphogenesis
Outflow Tract Morphogenesis
Regulation Of DNA-templated Transcription
Segment Specification
Heart Development
Intracellular Protein Localization
Wnt Signaling Pathway
Convergent Extension Involved In Neural Plate Elongation
Regulation Of Actin Cytoskeleton Organization
Segmentation
Intracellular Signal Transduction
Non-canonical Wnt Signaling Pathway
Regulation Of Cell Population Proliferation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of JNK Cascade
Convergent Extension Involved In Organogenesis
Canonical Wnt Signaling Pathway
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Cochlea Morphogenesis
Positive Regulation Of Neuron Projection Arborization
Positive Regulation Of Signal Transduction By P53 Class Mediator
System Development
Pathways
TCF dependent signaling in response to WNT
WNT mediated activation of DVL
Signaling by Hippo
PCP/CE pathway
PCP/CE pathway
Asymmetric localization of PCP proteins
Degradation of DVL
Disassembly of the destruction complex and recruitment of AXIN to the membrane
Disassembly of the destruction complex and recruitment of AXIN to the membrane
WNT5A-dependent internalization of FZD4
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
RHO GTPases Activate Formins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
WNT5:FZD7-mediated leishmania damping
WNT5:FZD7-mediated leishmania damping
Zygotic genome activation (ZGA)
Drugs
Diseases
GWAS
Metabolite levels (
31628463
)
Corneal astigmatism (
23761726
)
Spatial memory (
31596458
)
Interacting Genes
106 interacting genes:
ABL1
AKAP9
AP1M1
AP2M1
AQP9
ARHGEF39
ARR3
ARRB1
ARRB2
ATN1
AXIN1
BAG3
BAHD1
BCL6
BEND7
BYSL
CARD9
CCDC33
CPSF7
CSNK1E
CTBP2
CUL1
DAAM1
DCUN1D1
DDI1
DPPA2
DYNLT1
EIF1B
ELOA2
ENKD1
FAM161A
FAM90A1
FZD4
GABARAP
GABARAPL1
GMCL2
GOLGA2
GRAP2
GRB2
HIP1
IHO1
LMO3
LRRK2
MAGOHB
MAP1LC3A
MCRS1
NOL12
NUP62CL
NUP88
OTULIN
PARD6A
PCBD1
PLA2G12A
POLI
PPM1A
PPP1R16B
PRKAA1
PRKCA
PRKCB
PRKCG
PRPF3
PRPF31
PSMF1
RAC1
RAP1B
RBFOX1
RBPMS
RHOA
RHOXF2
RNF185
RNPS1
RUNX2
RUSC1
SCNM1
SMURF1
SNF8
SNIP1
SORBS3
SSX2IP
TAB1
TDP2
THAP1
TIFA
TLE5
TP53
TPM3
TRAF2
U2AF2
UBAC1
UIMC1
USP5
USP9X
VANGL1
VHL
WAS
WT1
WWP2
YES1
ZBTB48
ZBTB8A
ZGPAT
ZNF165
ZNF250
ZNF263
ZNF410
ZNF581
19 interacting genes:
AP2M1
DPPA4
DVL2
DVL3
EIF1AD
FGF12
FXR2
MCM10
MOAP1
PBXIP1
PLOD3
SDCBP2
SETD5
SPOP
U2AF2
UBE2I
VTA1
ZCCHC10
ZNF250
Entrez ID
1856
151871
HPRD ID
03690
13248
Ensembl ID
ENSG00000004975
ENSG00000163530
Uniprot IDs
O14641
Q7Z7J5
PDB IDs
2REY
3CBX
3CBY
3CBZ
3CC0
4WIP
5LNP
5SUY
5SUZ
6IW3
6JCK
8WM9
8WMA
8WWR
8YR7
Enriched GO Terms of Interacting Partners
?
Protein Binding
Regulation Of RNA Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Nucleus
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Non-canonical Wnt Signaling Pathway
Positive Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Wnt Signaling Pathway
Regulation Of Signal Transduction
Intracellular Signaling Cassette
Negative Regulation Of Macromolecule Metabolic Process
Regulation Of Intracellular Signal Transduction
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Regulation Of Protein Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Cytosol
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Regulation Of Protein Modification Process
Nucleoplasm
Cytoplasm
Regulation Of Signaling
Regulation Of Cell Communication
Regulation Of Protein Ubiquitination
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Protein Modification Process
Cellular Component Assembly
Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Macromolecule Biosynthetic Process
Enzyme Binding
Cytoskeleton
Regulation Of Transcription By RNA Polymerase II
Intracellular Signal Transduction
Macromolecule Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of MAPK Cascade
Negative Regulation Of RNA Metabolic Process
Post-translational Protein Modification
Autophagy
Positive Regulation Of Neuron Projection Arborization
Regulation Of Neuron Projection Arborization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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