DNASE1 and TSC22D1

		DNASE1	TSC22D1
Description		deoxyribonuclease 1	TSC22 domain family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nuclear Envelope Cytoplasmic Vesicle Zymogen Granule Extracellular Exosome	Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane
	Molecular Function	DNA Binding Actin Binding Catalytic Activity Nuclease Activity Endonuclease Activity Deoxyribonuclease I Activity DNA Nuclease Activity Protein Binding Hydrolase Activity	Transcription Coactivator Activity Protein Binding Identical Protein Binding
	Biological Process	Neutrophil Activation Involved In Immune Response Regulation Of Acute Inflammatory Response DNA Catabolic Process Apoptotic Process Regulation Of Neutrophil Mediated Cytotoxicity	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Negative Regulation Of Hematopoietic Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 29273807) Monocyte percentage of white cells ( 32888494)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Body mass index ( 25760438) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)
Interacting Genes		5 interacting genes: ACTA1 ACTA2 ACTB ACTG1 TSC22D1	57 interacting genes: A2M APLP1 ASAH1 CACNA1A CARHSP1 CCDC88C CCDC90B CFTR CHD3 CKAP2 CORO2B CRMP1 DDAH2 DNASE1 DNMT3B EED ERG28 FAF1 FAM20C FBN3 GNB2 GNB5 GORASP2 GTF2F2 HMGXB4 KMT2B KMT2C LPAR6 LRIF1 MAP3K12 MCM3AP NCOA5 NTAQ1 OTUB1 PDHB PRKCI PTN QARS1 RFXAP RGS1 RPL5 SETDB1 SP110 SPACA9 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WIZ WNK1 ZC3HC1
Entrez ID		1773	8848
HPRD ID		00509	07414
Ensembl ID		ENSG00000213918	ENSG00000102804
Uniprot IDs		P24855	A8K3Y6 Q15714
PDB IDs		4AWN
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Mesenchyme Migration Regulation Of Transepithelial Transport Dense Body Actin Filament Structural Constituent Of Postsynaptic Actin Cytoskeleton Morphogenesis Of A Polarized Epithelium Structural Constituent Of Cytoskeleton Blood Microparticle Postsynaptic Actin Cytoskeleton Organization Protein Localization To Cell-cell Junction Calyx Of Held Lamellipodium Postsynaptic Cytoskeleton Organization Regulation Of Synaptic Vesicle Endocytosis NuA4 Histone Acetyltransferase Complex Apical Junction Complex Regulation Of Synaptic Vesicle Recycling Maintenance Of Blood-brain Barrier Positive Regulation Of Macromolecule Biosynthetic Process Platelet Aggregation Positive Regulation Of Biosynthetic Process Homotypic Cell-cell Adhesion Protein Kinase Binding Positive Regulation Of Macromolecule Metabolic Process ATP Binding Filopodium Cytoskeleton Cell Body Extracellular Space Stress Fiber Positive Regulation Of Hepatic Stellate Cell Contraction Protein Localization To Cell Junction Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Basal Body Patch Positive Regulation Of Metabolic Process Schaffer Collateral - CA1 Synapse Hydrolase Activity Nucleotide Binding Cell-cell Junction Assembly Positive Regulation Of Hepatic Stellate Cell Migration Regulation Of Norepinephrine Uptake Axonogenesis Juxtaglomerular Apparatus Development Transporter Regulator Activity Extracellular Exosome Cell-cell Junction Organization Glomerular Mesangial Cell Development Smooth Muscle Contractile Fiber	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Nucleus Nucleoplasm Negative Regulation Of Cell Communication Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Signaling Histone H3K4 Monomethyltransferase Activity Histone H3K4 Trimethyltransferase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?