TSC22D1 and FAM20C

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		TSC22D1	FAM20C
Description		TSC22 domain family member 1	FAM20C golgi associated secretory pathway kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane	Golgi Membrane Extracellular Region Extracellular Space Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Membrane Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Identical Protein Binding	Nucleotide Binding Protease Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Calcium Ion Binding Protein Binding ATP Binding Kinase Activity Transferase Activity Manganese Ion Binding Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Negative Regulation Of Hematopoietic Stem Cell Proliferation	Skeletal System Development Protein Phosphorylation Positive Regulation Of Bone Mineralization Biomineral Tissue Development Osteoclast Maturation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Post-translational Protein Modification Positive Regulation Of Osteoblast Differentiation Regulation Of Phosphorus Metabolic Process Enamel Mineralization Odontoblast Differentiation Dentinogenesis
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases			Raine syndrome; Lethal osteosclerotic bone dysplasia
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Body mass index ( 25760438) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)	Allergic rhinitis ( 25085501) Alzheimer's disease in APOE e4- carriers ( 25778476)
Interacting Genes		57 interacting genes: A2M APLP1 ASAH1 CACNA1A CARHSP1 CCDC88C CCDC90B CFTR CHD3 CKAP2 CORO2B CRMP1 DDAH2 DNASE1 DNMT3B EED ERG28 FAF1 FAM20C FBN3 GNB2 GNB5 GORASP2 GTF2F2 HMGXB4 KMT2B KMT2C LPAR6 LRIF1 MAP3K12 MCM3AP NCOA5 NTAQ1 OTUB1 PDHB PRKCI PTN QARS1 RFXAP RGS1 RPL5 SETDB1 SP110 SPACA9 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WIZ WNK1 ZC3HC1	8 interacting genes: FAM118B P4HB PFDN1 SMN1 SUV39H2 TAF1D TK1 TSC22D1
Entrez ID		8848	56975
HPRD ID		07414	13298
Ensembl ID		ENSG00000102804	ENSG00000177706
Uniprot IDs		A8K3Y6 Q15714	Q8IXL6
PDB IDs			5YH3
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Nucleus Nucleoplasm Negative Regulation Of Cell Communication Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Signaling Histone H3K4 Monomethyltransferase Activity Histone H3K4 Trimethyltransferase Activity	Cellular Response To Decreased Oxygen Levels Procollagen-proline 4-dioxygenase Activity Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Cellular Response To Oxygen Levels Cellular Response To Hypoxia Peptidyl-proline Hydroxylation Procollagen-proline 4-dioxygenase Complex Cajal Body Identical Protein Binding DNA Synthesis Involved In Mitotic DNA Replication Thymidine Biosynthetic Process Thymidine Kinase Activity Negative Regulation Of Hematopoietic Stem Cell Proliferation RNA Polymerase Transcription Factor SL1 Complex Histone H3K9 Trimethyltransferase Activity Interleukin-23-mediated Signaling Pathway Thiol Oxidase Activity Prefoldin Complex Thymidine Metabolic Process Protein Folding Insulin Processing Interleukin-12-mediated Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process
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