TSC22D1 and ZC3HC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		TSC22D1	ZC3HC1
Description		TSC22 domain family member 1	zinc finger C3HC-type containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane	Nucleus Nuclear Envelope Nucleoplasm Nuclear Membrane Nuclear Pore Nuclear Basket
	Molecular Function	Transcription Coactivator Activity Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding Protein Kinase Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Programmed Cell Death Positive Regulation Of DNA-templated Transcription Negative Regulation Of Hematopoietic Stem Cell Proliferation	Protein Ubiquitination Cell Division
Pathways			Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Body mass index ( 25760438) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)	Coronary artery disease ( 24262325 26343387 33020668 32469254 29212778) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Coronary artery disease or ischemic stroke ( 24262325) Coronary artery disease or large artery stroke ( 24262325) Coronary heart disease ( 21378990) Diastolic blood pressure ( 27618452 27841878) Eosinophil count ( 32888494) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Myocardial infarction ( 33532862 26343387) Neutrophil count ( 32888494) Parental lifespan ( 30642433) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Red cell distribution width ( 32888494) Systolic blood pressure ( 28739976 27841878 27618452) White blood cell count ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		57 interacting genes: A2M APLP1 ASAH1 CACNA1A CARHSP1 CCDC88C CCDC90B CFTR CHD3 CKAP2 CORO2B CRMP1 DDAH2 DNASE1 DNMT3B EED ERG28 FAF1 FAM20C FBN3 GNB2 GNB5 GORASP2 GTF2F2 HMGXB4 KMT2B KMT2C LPAR6 LRIF1 MAP3K12 MCM3AP NCOA5 NTAQ1 OTUB1 PDHB PRKCI PTN QARS1 RFXAP RGS1 RPL5 SETDB1 SP110 SPACA9 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WIZ WNK1 ZC3HC1	11 interacting genes: ALK APP CUL1 MAPK3 PDPK1 TNFSF11 TPR TRIM55 TRIM63 TSC22D1 YWHAE
Entrez ID		8848	51530
HPRD ID		07414	11390
Ensembl ID		ENSG00000102804	ENSG00000091732
Uniprot IDs		A8K3Y6 Q15714	C9J0I9 Q86WB0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Nucleus Nucleoplasm Negative Regulation Of Cell Communication Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Signaling Histone H3K4 Monomethyltransferase Activity Histone H3K4 Trimethyltransferase Activity	Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Intracellular Signal Transduction Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Response To Epidermal Growth Factor Intracellular Signaling Cassette Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Response To Stress Peptidyl-tyrosine Autophosphorylation Response To Cytokine Response To Peptide Protein Modification Process Identical Protein Binding Regulation Of Non-canonical NF-kappaB Signal Transduction Response To Growth Factor Immune System Process Protein Autophosphorylation Negative Regulation Of Catabolic Process Protein Metabolic Process Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Defense Response Positive Regulation Of Transport Regulation Of Calcium Ion Transmembrane Transport Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Cell Development Positive Regulation Of Protein Localization Calcium-mediated Signaling Positive Regulation Of Defense Response Positive Regulation Of Inflammatory Response Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Regulation Of Immune System Process Regulation Of Transport Positive Regulation Of ERK1 And ERK2 Cascade Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Immune System Process Regulation Of Cellular Localization Negative Regulation Of Immune System Process Regulation Of Protein Export From Nucleus Positive Regulation Of Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
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