AK8 and MID1IP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		AK8	MID1IP1
Description		adenylate kinase 8	MID1 interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Axoneme Sperm Flagellum Cell Projection 9+2 Motile Cilium	Nucleus Cytoplasm Cytosol Cytoskeleton Microtubule Microtubule Cytoskeleton
	Molecular Function	Nucleotide Binding AMP Kinase Activity Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding AMP Binding Kinase Activity Transferase Activity Phosphotransferase Activity, Phosphate Group As Acceptor Nucleobase-containing Compound Kinase Activity DCMP Kinase Activity	Protein Binding Enzyme Activator Activity Identical Protein Binding Ligase Regulator Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Nucleotide Metabolic Process Nucleoside Monophosphate Metabolic Process Ventricular System Development Nucleoside Monophosphate Phosphorylation	Lipid Metabolic Process Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Fatty Acid Biosynthetic Process Regulation Of Lipid Biosynthetic Process Protein Polymerization Positive Regulation Of Ligase Activity
Pathways		Interconversion of nucleotide di- and triphosphates	Carnitine shuttle
Drugs		Bis(Adenosine)-5'-Pentaphosphate
Diseases
GWAS		Obesity-related traits ( 23251661)	Response to metformin (IC50) ( 28173075)
Interacting Genes		18 interacting genes: ALKBH3 CCDC102B CDK18 CFTR CNTF DPY30 FBXO7 HAUS1 MAP3K7CL MCM7 MID1IP1 PRMT6 PRRC2B RBM39 SMG9 SYT17 UBE2Z ZMAT2	7 interacting genes: AK8 APOE GSK3B MID1 MID2 SUFU TSHR
Entrez ID		158067	58526
HPRD ID		12991	06732
Ensembl ID		ENSG00000165695	ENSG00000165175
Uniprot IDs		Q96MA6	Q9NPA3
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Phospholipid Efflux Tau Protein Binding Enzyme Binding Artery Development Negative Regulation Of Postsynaptic Membrane Organization Positive Regulation Of Lipid Transport Across Blood-brain Barrier Negative Regulation Of Lipid Transport Across Blood-brain Barrier Response To Amyloid-beta Regulation Of Cellular Response To Very-low-density Lipoprotein Particle Stimulus Regulation Of Proteolysis Negative Regulation Of Protein Localization Regulation Of Long-term Synaptic Potentiation Cellular Response To Amyloid-beta Metal Chelating Activity Intermediate-density Lipoprotein Particle Clearance Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Protein Localization To Nucleus Regulation Of Microtubule Anchoring At Centrosome Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Localization To Microtubule Protein Localization To Cytoskeleton Phosphoprotein Binding Cellular Response To Thyrotropin-releasing Hormone Regulation Of Cellular Response To Drug Positive Regulation Of Cellular Response To Drug Regulation Of Axon Extension Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Presynaptic Membrane Organization Chylomicron Remnant Host-mediated Perturbation Of Symbiont Process Positive Regulation Of Intracellular Signal Transduction Lipid Transport Involved In Lipid Storage Lipoprotein Particle Regulation Of Protein Transport Positive Regulation Of Neurofibrillary Tangle Assembly Discoidal High-density Lipoprotein Particle Beta-catenin Binding Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Thyroid-stimulating Hormone Receptor Activity Thyroid-stimulating Hormone Signaling Pathway Response To Thyrotropin-releasing Hormone Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Positive Regulation Of Response To Drug Regulation Of Establishment Of Protein Localization Modulation Of Process Of Another Organism Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Protein Transport
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