WFDC12 and TP53TG5

		WFDC12	TP53TG5
Description		WAP four-disulfide core domain 12	TP53 target 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Nucleus Chromosome Nucleolus Cytoplasm
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity	Protein Binding
	Biological Process	Antibacterial Humoral Response Defense Response To Bacterium Innate Immune Response	Negative Regulation Of Cell Growth Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756 34002096)	Malaria ( 31844061)
Interacting Genes		12 interacting genes: ADA ASPH MMP9 NNAT RBPJL SGTA SGTB SLC39A7 SULF2 TP53TG5 UBQLN1 UBQLN2	3 interacting genes: APP CD40 WFDC12
Entrez ID		128488	27296
HPRD ID		15674	12733
Ensembl ID		ENSG00000168703	ENSG00000124251
Uniprot IDs		Q8WWY7	B4DHX6 Q9Y2B4
PDB IDs
Enriched GO Terms of Interacting Partners?		TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Transport Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Muscle Contraction Regulation Of Transport Regulation Of Proteasomal Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Protein Catabolic Process Smooth Muscle Contraction Mature B Cell Apoptotic Process Negative Regulation Of Adenosine Receptor Signaling Pathway Muscle System Process 2'-deoxyadenosine Deaminase Activity Xanthine Biosynthetic Process Negative Regulation Of Penile Erection Regulation Of Monoatomic Cation Transmembrane Transport Response To Endoplasmic Reticulum Stress Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Germinal Center Formation Negative Regulation Of Mucus Secretion Mononuclear Cell Differentiation Inosine Biosynthetic Process Penile Erection Hypoxanthine Salvage DATP Catabolic Process Peptidyl-aspartic Acid 3-dioxygenase Activity Negative Regulation Of Cation Transmembrane Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Protein Targeting To Membrane Negative Regulation Of G Protein-coupled Receptor Internalization Esophagus Smooth Muscle Contraction Autophagosome Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Mature B Cell Apoptotic Process B Cell Differentiation DATP Metabolic Process	Response To Bacterium Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Immune Response Response To Interleukin-1 Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Defense Response To Other Organism Amylin Binding Endosome To Plasma Membrane Transport Vesicle Antibacterial Humoral Response Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Defense Response Response To External Biotic Stimulus Lipoprotein Particle Peptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity Response To Mechanical Stimulus Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Antimicrobial Humoral Response Positive Regulation Of Protein Import Response To Other Organism Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Interleukin-4-mediated Signaling Pathway Positive Regulation Of Protein Kinase C Signaling Response To Cobalamin Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Extracellular Space Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Humoral Immune Response Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Protein Kinase C Signaling Response To Erythropoietin Cellular Response To Erythropoietin Defense Response To Bacterium Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway
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