C12orf57 and ANKK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C12orf57	ANKK1
Description		chromosome 12 open reading frame 57	ankyrin repeat and kinase domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Nuclear Speck	Nucleus Cytoplasm Cell Projection
	Molecular Function	Protein Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Post-embryonic Development Regulation Of Skeletal Muscle Contraction Corpus Callosum Morphogenesis Third Ventricle Development Psychomotor Behavior Camera-type Eye Morphogenesis Cognition	Regulation Of Cell Cycle Process Cellular Response To Retinoic Acid
Pathways
Drugs			Fostamatinib
Diseases
GWAS		Refractive error ( 32231278)	Alcohol consumption (drinks per week) ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 26426971) Experiencing mood swings ( 29500382)
Interacting Genes		2 interacting genes: ANKK1 INSL3	4 interacting genes: C12orf57 CATSPERT CHN1 CHN2
Entrez ID		113246	255239
HPRD ID		13609	10580
Ensembl ID		ENSG00000111678	ENSG00000170209
Uniprot IDs		F5GXW5 Q99622 U3KQ85	Q8NFD2
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Small GTPase Mediated Signal Transduction GTPase Activator Activity Corpus Callosum Morphogenesis Psychomotor Behavior Third Ventricle Development CatSper Complex Motor Neuron Axon Guidance Ephrin Receptor Binding Developmental Process Acrosome Assembly Central Nervous System Projection Neuron Axonogenesis Central Nervous System Neuron Axonogenesis Regulation Of Skeletal Muscle Contraction Motor Behavior Camera-type Eye Morphogenesis Sperm Principal Piece Sperm Capacitation
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