ANKK1 and CHN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ANKK1	CHN1
Description		ankyrin repeat and kinase domain containing 1	chimerin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cell Projection	Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding Ephrin Receptor Binding
	Biological Process	Regulation Of Cell Cycle Process Cellular Response To Retinoic Acid	Signal Transduction Nervous System Development Motor Neuron Axon Guidance Ephrin Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction
Pathways			CDC42 GTPase cycle RAC1 GTPase cycle
Drugs		Fostamatinib
Diseases			Duane retraction syndrome
GWAS		Alcohol consumption (drinks per week) ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 26426971) Experiencing mood swings ( 29500382)	Post bronchodilator FEV1 ( 26634245)
Interacting Genes		4 interacting genes: C12orf57 CATSPERT CHN1 CHN2	16 interacting genes: ACVR1 ADORA2A ANKK1 BMPR1B CDK5 CDK5R1 ERBB2 GTF3C1 HEMK1 HTR6 MAPK1 MAPK8IP2 NCK2 RAC1 RPS3A TGFBR1
Entrez ID		255239	1123
HPRD ID		10580	00319
Ensembl ID		ENSG00000170209	ENSG00000128656
Uniprot IDs		Q8NFD2	P15882
PDB IDs			2OSA 3CXL
Enriched GO Terms of Interacting Partners?		Regulation Of Small GTPase Mediated Signal Transduction GTPase Activator Activity Corpus Callosum Morphogenesis Psychomotor Behavior Third Ventricle Development CatSper Complex Motor Neuron Axon Guidance Ephrin Receptor Binding Developmental Process Acrosome Assembly Central Nervous System Projection Neuron Axonogenesis Central Nervous System Neuron Axonogenesis Regulation Of Skeletal Muscle Contraction Motor Behavior Camera-type Eye Morphogenesis Sperm Principal Piece Sperm Capacitation	Protein Kinase Activity Transforming Growth Factor Beta Receptor Activity, Type I Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Communication Kinase Activity Positive Regulation Of Signaling Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Cell Projection Organization Transmembrane Receptor Protein Serine/threonine Kinase Activity Positive Regulation Of Signal Transduction Schwann Cell Development Regulation Of Apoptotic Signaling Pathway Protein Serine/threonine Kinase Activity Neuron Projection Guidance Axon Guidance Positive Regulation Of Protein Targeting To Membrane Motor Neuron Axon Guidance Dendrite Protein Kinase 5 Complex Cerebral Cortex Cell Migration Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Protein Targeting To Membrane Positive Regulation Of Apoptotic Process Cell Migration Response To Growth Factor Positive Regulation Of Programmed Cell Death Positive Regulation Of Establishment Of Protein Localization Chemical Synaptic Transmission Plasma Membrane Bounded Cell Projection Organization ErbB-3 Class Receptor Binding Telencephalon Cell Migration Growth Factor Binding Regulation Of Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway Forebrain Cell Migration Trans-synaptic Signaling SMAD Binding Synaptic Signaling Dendrite Morphogenesis Neuronal Cell Body Neuron Differentiation Regulation Of Protein Modification Process Positive Regulation Of Supramolecular Fiber Organization Activin Receptor Complex Activin Receptor Activity, Type I Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway
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