ACTL7B and DHX38

		ACTL7B	DHX38
Description		actin like 7B	DEAH-box helicase 38
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Actin Cytoskeleton	Nucleus Nucleoplasm Spliceosomal Complex Membrane Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On RNA Hydrolase Activity ATP Hydrolysis Activity 3'-5' RNA Helicase Activity
	Biological Process	Cytoskeleton Organization	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 33020668) Cotinine glucuronidation ( 25293881) Heel bone mineral density ( 30598549) Keratoconus ( 33649486) Metabolite levels ( 23823483) Paclitaxel-induced neuropathy ( 23776197)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Blood protein levels ( 23696881) Cholesterol, total ( 20686565 25961943) Coronary artery disease ( 29212778) Depression ( 29700475) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) LDL cholesterol ( 20686565 25961943) Medication use (HMG CoA reductase inhibitors) ( 31015401) Metabolite levels ( 22916037) Red blood cell count ( 32888494) Serum metabolite levels (CMS) ( 31636271) Urate levels ( 31578528)
Interacting Genes		3 interacting genes: APP CD276 DHX38	17 interacting genes: AARS1 ACTL7B BCO1 CDC40 CMTM3 CSNK2A1 CTCF E2F4 MFAP1 NDRG4 NOL3 PPP4C RNF10 SNRNP200 TNFRSF4 U2AF1 WBP4
Entrez ID		10880	9785
HPRD ID		11977	05720
Ensembl ID		ENSG00000148156	ENSG00000140829
Uniprot IDs		A0A140VKC6 Q9Y614	Q92620
PDB IDs			5YZG 6ZYM 7A5P 8I0W
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Type II Interferon Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Type II Interferon Production Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition External Side Of Plasma Membrane 3'-5' RNA Helicase Activity Heparan Sulfate Binding Signaling Receptor Activator Activity Signaling Receptor Binding Peptidase Activator Activity Positive Regulation Of Cell Activation Cellular Response To Manganese Ion ATP-dependent Activity, Acting On RNA Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding	MRNA Metabolic Process MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Processing U2-type Precatalytic Spliceosome RNA Metabolic Process Nucleic Acid Metabolic Process Catalytic Step 2 Spliceosome Nucleobase-containing Compound Metabolic Process RNA Binding Negative Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Cytoplasmic Translational Fidelity Response To Injury Involved In Regulation Of Muscle Adaptation Negative Regulation Of Muscle Atrophy Chromatin Loop Anchoring Activity Spliceosome Conformational Change To Release U4 (or U4atac) And U1 (or U11) Vitamin A Biosynthetic Process Beta-carotene Metabolic Process Nucleus Peptide Lactyltransferase (ATP-dependent) Activity Macromolecule Metabolic Process Ser-tRNA(Ala) Deacylase Activity Cis Assembly Of Pre-catalytic Spliceosome Carotene Metabolic Process Carotenoid Dioxygenase Activity Carotene Catabolic Process Nucleic Acid Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?