ACTL7B and CD276

		ACTL7B	CD276
Description		actin like 7B	CD276 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Actin Cytoskeleton	External Side Of Plasma Membrane Membrane
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Cytoskeleton Organization	Regulation Of Cytokine Production Positive Regulation Of Cytokine Production Regulation Of Type II Interferon Production Positive Regulation Of Type II Interferon Production Positive Regulation Of T Cell Proliferation T Cell Activation Regulation Of Immune Response T Cell Receptor Signaling Pathway
Pathways
Drugs			Omburtamab
Diseases
GWAS		Central corneal thickness ( 32528159) Coronary artery disease ( 33020668) Cotinine glucuronidation ( 25293881) Heel bone mineral density ( 30598549) Keratoconus ( 33649486) Metabolite levels ( 23823483) Paclitaxel-induced neuropathy ( 23776197)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Bipolar disorder ( 21738484 31043756) Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications ( 28100913) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757 33972514) Tourette syndrome ( 30818990)
Interacting Genes		3 interacting genes: APP CD276 DHX38	5 interacting genes: ACSBG1 ACTL7B BRD8 BRDT VPS26B
Entrez ID		10880	80381
HPRD ID		11977	05756
Ensembl ID		ENSG00000148156	ENSG00000103855
Uniprot IDs		A0A140VKC6 Q9Y614	A0A0C4DGH0 A8K9J6 Q5ZPR3
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Type II Interferon Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Type II Interferon Production Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition External Side Of Plasma Membrane 3'-5' RNA Helicase Activity Heparan Sulfate Binding Signaling Receptor Activator Activity Signaling Receptor Binding Peptidase Activator Activity Positive Regulation Of Cell Activation Cellular Response To Manganese Ion ATP-dependent Activity, Acting On RNA Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding
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