C2CD2L and IL3RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		C2CD2L	IL3RA
Description		C2CD2 like	interleukin 3 receptor subunit alpha
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Cortical Endoplasmic Reticulum Cytoplasmic Side Of Apical Plasma Membrane Endoplasmic Reticulum-plasma Membrane Contact Site	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Receptor Complex
	Molecular Function	Protein Binding Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Insulin Binding	Cytokine Receptor Activity Interleukin-3 Receptor Activity Protein Binding Cytokine Binding
	Biological Process	Phospholipid Transport Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Intermembrane Lipid Transfer	Cytokine-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-3-mediated Signaling Pathway
Pathways			Interleukin-3, Interleukin-5 and GM-CSF signaling RAF/MAP kinase cascade Interleukin receptor SHC signaling
Drugs			Sargramostim Tagraxofusp
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) Heel bone mineral density ( 30598549)	Schizophrenia ( 17522711)
Interacting Genes		32 interacting genes: AQP6 ARL13B ATP5MG CD79A CHODL CISD2 CLRN1 CPEB2 CXCR3 EBP EPB41 FCER1G GJA8 GJB1 HIBADH IL3RA MFSD5 MUC1 OPRM1 PDZK1IP1 REEP2 REEP4 SDCBP SLC10A6 SLC18A1 TMEM14B TMEM179B TMEM31 TMEM86B TMEM9 TMPRSS2 TMX2	32 interacting genes: BMP10 C2CD2L CDC25A CDK1 CISH CLDN19 CSF2 CSF2RB EMP3 FOXP1 GIMAP1 GNA12 IL3 JAGN1 JAK1 JAK2 LNX1 NINJ2 NR0B2 PAQR5 PPP1CC SAE1 SERP1 SGK2 SMAGP SYS1 TMEM128 TMEM147 TMEM254 TMEM65 TRARG1 VAMP5
Entrez ID		9854	3563
HPRD ID		15533	02392
Ensembl ID		ENSG00000172375	ENSG00000185291
Uniprot IDs		O14523	P26951
PDB IDs		5TOD	4JZJ 5UV8 5UWC 6NMY
Enriched GO Terms of Interacting Partners?
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