CDK1 and FEN1

  • Number of citations of the paper that reports this interaction (PubMedID 12853968)
  • 42

CDK1

FEN1

Description cyclin dependent kinase 1 flap structure-specific endonuclease 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cocaine dependence ( 23958962)
  • Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 31095298)
  • Asthma ( 31959851 31619474)
  • Bipolar disorder ( 28115744 31043756)
  • Bipolar I disorder ( 31043756)
  • Brain morphology (MOSTest) ( 32665545)
  • Colorectal cancer ( 24836286)
  • Colorectal cancer or advanced adenoma ( 30510241)
  • Crohn's disease ( 28067908)
  • Daytime nap ( 33568662)
  • Delta-5 desaturase activity response to n3-polyunsaturated fat supplement ( 29246731)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Hemoglobin levels ( 32327693)
  • Laryngeal squamous cell carcinoma ( 25194280)
  • Male-pattern baldness ( 28196072)
  • Metabolite levels ( 23823483 23378610)
  • Oleic acid (18:1n-9) levels ( 23362303)
  • Palmitoleic acid (16:1n-7) levels ( 23362303)
  • Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid) ( 21829377)
  • Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid) ( 21829377)
  • Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) ( 21829377)
  • Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid) ( 24823311)
  • Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid) ( 24823311)
  • Platelet count ( 22139419)
  • QT interval ( 29874175)
  • Red blood cell fatty acid levels ( 25500335)
  • Refractive error ( 32231278)
  • Resting heart rate ( 27798624)
  • Serum metabolite levels ( 23093944)
  • Serum metabolite ratios in chronic kidney disease ( 29545352)
  • Stearic acid (18:0) levels ( 23362303)
Interacting Genes 188 interacting genes: ABL1 AMPH APLP2 AR ARID4A BARD1 BCL2 BIRC5 BIRC6 BRCA1 BRCA2 BTRC BUB1 CALD1 CCNA1 CCNA2 CCNB1 CCNB1IP1 CCNB2 CCNE1 CCP110 CD8A CDC20 CDC25A CDC25B CDC25C CDC6 CDCA2 CDCA5 CDK7 CDKN1A CDKN1B CDKN3 CDT1 CEP55 CEP63 CHAF1B CIITA CKS2 CNOT7 CREM CSN2 CSNK2A1 CSNK2B CTNNB1 CUX1 CXCR1 DAB2 DCTN6 DNM2 DTL DUT E2F1 ECT2 EEF1D EEF2K EGFR EP300 EPN1 ERCC2 FANCA FANCC FANCG FBXO5 FEN1 FOXM1 FYN GADD45A GADD45B GADD45G GATA2 GBF1 GFAP GOLGA2 GORASP1 H1-0 H1-1 H1-3 H1-5 H2AC4 H2BC3 H4C1 HMGA1 HMGA2 HMGB1 HSPA2 HTRA2 IL16 IL3RA IPO13 ITGB3 ITPR1 JAK3 KAT5 KHDRBS1 KIF11 KIF20B KIF26B KMT2E KRT18 LATS1 LMNA LMNB1 LYN LZTS1 MAP4 MAPT MBP MCM4 MDM4 MEF2C MKI67 MLKL MNDA MYC MYT1 NCAPD2 NCAPG NCAPH NCL NDE1 NES NPM1 NSFL1C NUP210 PAK6 PBK PCNA PIN1 PITPNM1 PKMYT1 PLEC PML POLA1 PPP2R1A PPP2R1B PPP2R2B PRC1 PTCH1 PTMA PTPN1 PTPN2 PTPN6 PTTG1 RAB4A RAB5B RACGAP1 RAP1GAP RB1 RCC1 RELB REPS2 RFX3 RGCC RPA2 RPS6KB1 RRM2 RUNX1 RUNX2 SFN SP1 SPAG5 SQSTM1 SRC SSBP1 STK3 STMN1 STMN2 TFDP1 TGFBR2 TK1 TLE1 TNNC1 TOP2A TP53 TP53BP1 TP73 TSC1 TSPYL2 UBA1 UBE2A UBE3A UHRF2 USP16 VIM WEE1 XIAP ZBTB16 19 interacting genes: APEX1 APP ARHGDIA BLM CCNA2 CDK1 CDK2 EEF1G EP300 GSK3B HNRNPA1 HUS1 OGT PCNA RAD1 RAD9A TERF1 WDR4 WRN
Entrez ID 983 2237
HPRD ID 00302 02670
Ensembl ID ENSG00000170312 ENSG00000168496
Uniprot IDs A0A024QZJ8 B7Z3D6 I6L9I5 P06493 P39748 Q6FHX6
PDB IDs 1LC9 4Y72 4YC3 4YC6 5HQ0 5LQF 6GU2 6GU3 6GU4 6GU6 6GU7 1U7B 1UL1 3Q8K 3Q8L 3Q8M 3UVU 5E0V 5FV7 5K97 5KSE 5UM9 5ZOD 5ZOE 5ZOF 5ZOG 6TNZ
Enriched GO Terms of Interacting Partners?
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