MTSS1 and RECQL5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MTSS1	RECQL5
Description		MTSS I-BAR domain containing 1	RecQ like helicase 5
Image
GO Annotations	Cellular Component	Ruffle Cytoplasm Actin Cytoskeleton Endocytic Vesicle Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane	Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol RNA Polymerase II, Holoenzyme
	Molecular Function	Actin Binding Actin Monomer Binding Signaling Receptor Binding Protein Binding Phospholipid Binding Identical Protein Binding	RNA Polymerase II Complex Binding Nucleic Acid Binding DNA Helicase Activity ATP Binding Four-way Junction Helicase Activity ATP Hydrolysis Activity 3'-5' DNA Helicase Activity
	Biological Process	Plasma Membrane Organization Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Microspike Assembly Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Bundle Assembly Adherens Junction Maintenance Negative Regulation Of Epithelial Cell Proliferation Renal Tubule Morphogenesis Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis	Mitotic Cell Cycle Double-strand Break Repair Via Homologous Recombination DNA Metabolic Process DNA Replication DNA Unwinding Involved In DNA Replication DNA Repair DNA Recombination DNA Duplex Unwinding Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter Cell Division Chromosome Separation Cellular Response To Xenobiotic Stimulus Cellular Response To Camptothecin Replication-born Double-strand Break Repair Via Sister Chromatid Exchange Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Cognitive function ( 24684796) Cognitive performance in schizophrenia or bipolar disorder ( 31872970) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Dilated cardiomyopathy (MTAG) ( 33495596) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Irritable bowel syndrome ( 29626450) Left ventricle diastolic internal dimension ( 28394258) Left ventricular ejection fraction ( 33495596 31554410 32382064) Left ventricular end-systolic volume ( 33495596 32382064) Left ventricular global circumferential strain ( 33495596)	Deep white matter hyperintensities ( 32517579) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		4 interacting genes: HTT MZF1 PTPRD RECQL5	21 interacting genes: ADCY10P1 ALDH7A1 BNIPL CREB1 CUX1 DDX42 EEF1G ITGB3BP MAPK8IP1 MRE11 MTSS1 MUS81 NBN PCNA PLK1 RAD50 RAD51 STAMBP TIMP1 TOP3A TOP3B
Entrez ID		9788	9400
HPRD ID		12243	04806
Ensembl ID		ENSG00000170873	ENSG00000108469
Uniprot IDs		A5YM41 O43312	A0A024R8M9 A0A024R8S8 B3KQK2 O94762 Q8WYH5
PDB IDs		2D1K	4BK0 5LB3 5LB5 5LB8 5LBA
Enriched GO Terms of Interacting Partners?
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