MTSS1

Description		MTSS I-BAR domain containing 1
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GO Annotations	Cellular Component	Ruffle Cytoplasm Actin Cytoskeleton Endocytic Vesicle Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane
	Molecular Function	Actin Binding Actin Monomer Binding Signaling Receptor Binding Protein Binding Phospholipid Binding Identical Protein Binding
	Biological Process	Plasma Membrane Organization Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Microspike Assembly Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Bundle Assembly Adherens Junction Maintenance Negative Regulation Of Epithelial Cell Proliferation Renal Tubule Morphogenesis Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Nephron Tubule Epithelial Cell Differentiation Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Cognitive function ( 24684796) Cognitive performance in schizophrenia or bipolar disorder ( 31872970) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Dilated cardiomyopathy (MTAG) ( 33495596) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Irritable bowel syndrome ( 29626450) Left ventricle diastolic internal dimension ( 28394258) Left ventricular ejection fraction ( 33495596 31554410 32382064) Left ventricular end-systolic volume ( 33495596 32382064) Left ventricular global circumferential strain ( 33495596)
Interacting Genes		4 interacting genes: HTT MZF1 PTPRD RECQL5
Entrez ID		9788
HPRD ID		12243
Ensembl ID		ENSG00000170873
Uniprot IDs		A5YM41 O43312
PDB IDs		2D1K
Enriched GO Terms of Interacting Partners?
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