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RECQL5 and RAD51
Number of citations of the paper that reports this interaction (PubMedID
20348101
)
48
Data Source:
BioGRID
(pull down)
RECQL5
RAD51
Description
RecQ like helicase 5
RAD51 recombinase
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Chromosome
Cytoplasm
Cytosol
RNA Polymerase II, Holoenzyme
Nuclear Chromosome
Chromosome, Telomeric Region
Chromatin
Condensed Chromosome
Condensed Nuclear Chromosome
Lateral Element
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Microtubule Organizing Center
PML Body
Protein-containing Complex
Site Of Double-strand Break
Perinuclear Region Of Cytoplasm
Molecular Function
RNA Polymerase II Complex Binding
Nucleic Acid Binding
DNA Helicase Activity
ATP Binding
Four-way Junction Helicase Activity
ATP Hydrolysis Activity
3'-5' DNA Helicase Activity
DNA Strand Exchange Activity
Chromatin Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Protein Binding
ATP Binding
Protein C-terminus Binding
ATP-dependent Activity, Acting On DNA
Single-stranded DNA Helicase Activity
Enzyme Binding
Identical Protein Binding
DNA Polymerase Binding
Biological Process
Mitotic Cell Cycle
Double-strand Break Repair Via Homologous Recombination
DNA Metabolic Process
DNA Replication
DNA Unwinding Involved In DNA Replication
DNA Repair
DNA Recombination
DNA Duplex Unwinding
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Cell Division
Chromosome Separation
Cellular Response To Xenobiotic Stimulus
Cellular Response To Camptothecin
Replication-born Double-strand Break Repair Via Sister Chromatid Exchange
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomere Maintenance Via Recombination
Double-strand Break Repair Via Homologous Recombination
DNA Recombinase Assembly
Regulation Of Protein Phosphorylation
DNA Unwinding Involved In DNA Replication
DNA Repair
DNA Recombination
Mitotic Recombination
Cellular Response To DNA Damage Stimulus
Reciprocal Meiotic Recombination
Response To Xenobiotic Stimulus
Response To Toxic Substance
Response To X-ray
Regulation Of Double-strand Break Repair Via Homologous Recombination
Telomere Maintenance Via Telomere Lengthening
Replication Fork Processing
Interstrand Cross-link Repair
Strand Invasion
Positive Regulation Of DNA Ligation
Meiotic Cell Cycle
Chromosome Organization Involved In Meiotic Cell Cycle
Cellular Response To Ionizing Radiation
Cellular Response To Gamma Radiation
Cellular Response To Hydroxyurea
Cellular Response To Cisplatin
Cellular Response To Camptothecin
Response To Glucoside
Replication-born Double-strand Break Repair Via Sister Chromatid Exchange
Mitotic Recombination-dependent Replication Fork Processing
Pathways
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)
Resolution of D-loop Structures through Holliday Junction Intermediates
Homologous DNA Pairing and Strand Exchange
Presynaptic phase of homologous DNA pairing and strand exchange
Transcriptional Regulation by E2F6
Meiotic recombination
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function
Drugs
Phosphoaminophosphonic Acid-Adenylate Ester
Amuvatinib
Diseases
GWAS
Deep white matter hyperintensities (
32517579
)
Gut microbiota (bacterial taxa, hurdle binary method) (
32572223
)
Periventricular white matter hyperintensities (
32517579
)
Anxiety and stress-related disorders (
31116379
)
Hip circumference adjusted for BMI (
34021172
)
Malaria (
31844061
)
Mean spheric corpuscular volume (
32888494
)
Refractive error (
32231278
)
Interacting Genes
21 interacting genes:
ADCY10P1
ALDH7A1
BNIPL
CREB1
CUX1
DDX42
EEF1G
ITGB3BP
MAPK8IP1
MRE11
MTSS1
MUS81
NBN
PCNA
PLK1
RAD50
RAD51
STAMBP
TIMP1
TOP3A
TOP3B
95 interacting genes:
-
ABL1
AGO2
ATM
ATRX
BARD1
BCCIP
BCR
BLM
BRCA1
BRCA2
C1orf112
CASP3
CASP7
CCND1
CDH13
CHD3
CHEK1
CSNK2A1
CSNK2B
CST6
CTCF
DDB2
DMC1
DNAJA3
DYRK1A
ENAH
EP400
ERCC2
ERCC5
EVL
FANCD2
FANCI
FBH1
FIGNL1
HID1
HNRNPC
HSP90AA1
IL24
IRS1
ITIH5
MAPK8IP3
MDC1
MMS22L
MND1
MSH4
NBN
NCL
NELFB
NXF1
PALB2
PARPBP
PCSK1N
PDS5B
PFN1
PLK1
POLA1
RAD18
RAD51AP1
RAD51AP2
RAD51B
RAD51C
RAD52
RAD54B
RAD54L
RECQL5
RELA
RFWD3
RPA1
RPA2
RPA3
SEM1
SFR1
SIRT2
ST14
SUMO1
SUMO2
SWSAP1
TFF1
TP53
TP53BP1
UBE2I
UCHL3
UGDH
UHRF2
UMPS
USP10
VASP
VIM
WDR48
WRN
XPO1
XRCC2
XRCC3
ZDHHC17
Entrez ID
9400
5888
HPRD ID
04806
01557
Ensembl ID
ENSG00000108469
ENSG00000051180
Uniprot IDs
A0A024R8M9
A0A024R8S8
B3KQK2
O94762
Q8WYH5
Q06609
PDB IDs
4BK0
5LB3
5LB5
5LB8
5LBA
1B22
1N0W
5H1B
5H1C
5JZC
5NP7
5NWL
7C9A
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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